Researcher
Pieter Van Vlierberghe
- Keywords:acute lymfoblastic leukemia
- Disciplines:Cell signalling, Cancer therapy, Epigenetics, Cancer biology
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 29 Dec 2022 - Department of Pediatrics and medical genetics (Department)
Member
From1 Sep 2007 → 30 Sep 2018
Projects
1 - 10 of 59
- Role of TET2 in (pre)-leukemic T-ALL: TET2 to the rescueFrom1 Mar 2023 → 29 Feb 2024Funding: BOF - doctoral mandates
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- The role of SOX11 in T-cell acute lymphoblastic leukemiaFrom1 Jan 2023 → 31 Dec 2023Funding: BOF - doctoral mandates
- Preclinical validation of a less toxic variant for paediatric leukemiaFrom1 Oct 2022 → 30 Sep 2023Funding: Nonprofit institution or equivalents
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Functional analysis of the RNA helicase DHX15 in T-cell acutelymphoblastic leukemiaFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- An alternative more tolerable L-asparaginase variant for the treatment of metastatic breast cancerFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
- Targeting IL4 signaling as a novel therapeutic strategy in the treatment of T-cell acute lymphoblastic leukemiaFrom1 Oct 2021 → TodayFunding: BOF - projects
Publications
11 - 20 of 193
- Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL : focus on miR-363-3p and promoter methylation(2022)
Authors: Monika Drobna-Sledzinska, Natalia Mackowska-Maslak, Roman Jaksik, Maria Kosmalska, Bronislawa Szarzynska, Monika Lejman, Lukasz Sedek, Tomasz Szczepanski, Tom Taghon, Pieter Van Vlierberghe, et al.
Pages: 720 - 733 - ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells(2022)
Authors: Hila Fishman, Shreyas Madiwale, Ifat Geron, Vase Bari, Wouter Van Loocke, Yael Kirschenbaum, Itamar Ganmore, Eitan Kugler, Avigail Rein-Gil, Gilgi Friedlander, et al.
Pages: 399 - 412 - Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia(2022)
Authors: Qi Jin, Blanca Gutierrez Diaz, Yalu Zhou, Sonali Narang, Cristina Borin, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, et al.
- Myb drives B-cell neoplasms and myeloid malignancies in vivo(2022)
Authors: Kelly Lemeire, Tino Hochepied, Alex Kentsis, Pieter Van Vlierberghe
Pages: 2987 - 2991 - MDACT : a new principle of adjunctive cancer treatment using combinations of multiple repurposed drugs, with an example regimen(2022)
Authors: Richard E. Kast, Alex Alfieri, I Assi, Hazem, Terry C. Burns, Ashraf M. Elyamany, Maria Gonzalez-Cao, Georg Karpel-Massler, Christine Marosi, Michael E. Salacz, Iacopo Sardi, et al.
- Novel insights on the use of L-asparaginase as an efficient and safe anti-cancer therapy(2022)
Authors: Maaike Van Trimpont, Evelien Peeters, Yanti De Visser, Amanda M. Schalk, Veerle Mondelaers, Barbara De Moerloose, Arnon Lavie, Tim Lammens, Steven Goossens, Pieter Van Vlierberghe
- An interactive mass spectrometry atlas of histone posttranslational modifications in T-cell acute leukemia(2022)
Authors: Lien Provez, Bart Van Puyvelde, Laura Corveleyn, Nina Demeulemeester, Sigrid Verhelst, Beatrice Lintermans, Simon Daled, Juliette Roels, Lieven Clement, Lennart Martens, et al.
- Engraftment of allotransplanted tumor cells in adult rag2 mutant Xenopus tropicalis(2022)
Authors: Dieter Tulkens, Dionysia Dimitrakopoulou, Marthe Boelens, Tom Van Nieuwenhuysen, Suzan Demuynck, Wendy Toussaint, Pieter Van Vlierberghe, Kris Vleminckx
- SOX11 as guardian of epigenetic plasticity in neuroblastoma(2021)
Authors: Bieke Decaesteker, Amber Louwagie, Sara De Brouwer, Geertrui Denecker, Fanny De Vloed, Karen Verboom, Wouter Van Loocke, Elena Afanasyeva, Volodimir Olexiouk, Pauline Depuydt, et al.
Number of pages: 1 - PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis(2021)
Authors: E. G. Garcia, A. Veloso, M. L. Oliveira, J. R. Allen, S. Loontiens, D. Brunson, D. Do, C. Yan, R. Morris, S. Iyer, et al.
Pages: 679 - 690
Patents
1 - 1 of 1