Researcher
Patrick Matthys
- Disciplines:Immunology
Affiliations
- Immunobiology (Rega Institute) (Lab)
Responsible
From1 Oct 2021 → Today - Immunobiology (Rega Institute) (Lab)
Member
From1 Oct 1999 → Today
Projects
21 - 30 of 30
- Analysis of the functioning of natural killer (NK) cells and NK cell stimulating cytokines in disorders associated with secondary hemophagocytic lymphohistiocytosis.From1 Sep 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
- IL-10 in the pathogenesis of systemic juvenile idiopathic arthritis and regulation of its production by IFN-y in TLR-triggered inflammationFrom1 Oct 2014 → 5 Oct 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Innate immune mechanisms in infection, inflammation and cancer.From1 Jan 2013 → 31 Dec 2017Funding: BOF - Concerted Research Project from 1994
- Pathogenesis and therapy of the macrophage activation syndrome in virus-induced mouse models.From1 Oct 2012 → 24 Mar 2017Funding: IWT personal funding - strategic basic research grants
- Search for the pathogenesis of Macrophage Activation Syndrome (MAS) in systemic Juvenile Idiopathic Arthritis (sJIA): a translational study with a focus on innate immunity and IFN-gamma.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Macrophage activation syndrome in systemic juvenile idiopathic arthritis: analysis of abnormalities in interferon-gamma (IFN-g) and critical role of suppressor of cytokine signaling-m (SOC-3).From1 Oct 2011 → 26 Oct 2015Funding: FWO fellowships
- Macrophage activation syndrome in IFN-gamma-deficient mice: key role of natural killer cells and role of defective IFN-gamma signaling.From1 Oct 2010 → 30 Sep 2014Funding: FWO fellowships
- Genetic and cellular characterisation of Foxp3+ regulatory T cells during health and disease.From24 Nov 2009 → 20 Oct 2014Funding: IWT personal funding - strategic basic research grants
- Novel macrophage and myeloid dendritic cell markers for in vivo imaging and therapy of inflammatory disseases, inflammation tracking.(INFLAMMATRACK)From1 Jan 2009 → 31 Dec 2012Funding: SBO (Strategic basic research)
Publications
1 - 10 of 102
- Immunomodulation of wound healing(2023)
Authors: Rafaela Vaz Sousa Pereira, Ghislain Opdenakker, Patrick Matthys, Jan Vranckx
- Biallelic mutations in the CFHR genes underlying atypical hemolytic uremic syndrome in a patient with catastrophic adult-onset Still's disease and recurrent macrophage activation syndrome: A case report(2023)
Authors: Luna Dillemans, Youri Bekhuis, Lien De Somer, Patrick Matthys, Jeroen Breckpot, Thomas Tousseyn, Marijke Peetermans, Paul Proost, Carine Wouters, Steven Vanderschueren
- Multinucleated Giant Cell and Granuloma Formation Advances in Understanding(2023)
Authors: Kourosh Ahmadzadeh, Carine Wouters, Patrick Matthys
- Homozygous DBF4 mutation as a cause of severe congenital neutropenia(2023)
Authors: Frederik Staels, Margaux Gerbaux, Julika Neumann, Emanuela Pasciuto, Nancy Boeckx, Amber De Visscher, Patrick Matthys, Rik Schrijvers, Thomas Tousseyn, Giorgia Bucciol, et al.
Pages: 266 - 277 - TET2-Driver and NLRC4-Passenger Variants in Adult-Onset Autoinflammation(2023)
Authors: Ellen De Langhe, Frederik Staels, Raf Sciot, Olga Tsuiko, Mieke Gouwy, Patrick Verschueren, Carine Wouters, Paul Proost, Patrick Matthys, Eric Legius, et al.
Pages: 1626 - 1629 - Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing(2023)
Authors: Mostafa Ezeldeen, Jennifer Vandooren, Jan Vranckx, Patrick Matthys, Ghislain Opdenakker
- Multinucleation resets human macrophages for specialized functions at the expense of their identity (vol 24, e56310, 2023)(2023)
Authors: Kourosh Ahmadzadeh, Margot Vanoppen, Eline Bernaerts, Christy Maksoudian, Bella Manshian, Stefaan Soenen, Patrick Matthys, Carine Wouters
- Multinucleation resets human macrophages for specialized functions at the expense of their identity(2023)
Authors: Kourosh Ahmadzadeh, Margot Vanoppen, Eline Bernaerts, Christy Maksoudian, Bella Manshian, Stefaan Soenen, Patrick Matthys, Carine Wouters
- Novel method to quantify peptidylarginine deiminase activity shows distinct citrullination patterns in rheumatoid and juvenile idiopathic arthritis(2023)
Authors: Luna Dillemans, Mieke Gouwy, Patrick Matthys, Xavier Bossuyt, Patrick Verschueren, Carine Wouters, Lien De Somer, Paul Proost
- IRF2 is required for development and functional maturation of human NK cells(2022)
Authors: Patrick Matthys