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Researcher
Mathieu Bollen
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 39
- Phospho-regulation at the crossroads of cell proliferation and DNA-damage controlFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Coordination of cell-cycle progression and DNA-damage repair by the protein phosphatase-1 regulator NIPP1From1 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Life-course regulators of protein phosphatase-1From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Host cell phosphatases in the life cycle of DNA virusesFrom1 Oct 2020 → TodayFunding: BOF - projects
- Dual function of SDS22 in the biogenesis of protein phosphatase-1 holoenzymesFrom14 Oct 2019 → 14 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of histone modifications in the life cycle of AAV2 and recombinant AAV-mediated transgene expressionFrom1 Oct 2019 → 27 Jan 2023Funding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- Chaperone-mediated biogenesis and activity regulation of protein phosphatase-1From3 Sep 2019 → 10 Jan 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting a timer-integrator of cell checkpoint signaling for mesothelioma therapyFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Targeting a timer-integrator of cell checkpoint signaling for mesothelioma therapyFrom1 Jan 2019 → 31 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular timers of the spindle assembly checkpointFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 113
- Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice.(2024)
Authors: Marloes Jonkhout, Tijs Vanhessche, Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: S0022-202X - DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1(2024)
Authors: Aleyde Van Eynde, Mathieu Bollen
- Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections(2024)
Authors: Mathieu Bollen
- A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions(2023)
Authors: Mathieu Bollen
- A deficiency of PPP1R7 (SDS22) results in a loss of protein phosphatase-1 and is associated with a human neurodevelopmental disease(2023)
Authors: Mathieu Bollen
Pages: 224 - 224 - Substrate mapping and activity regulation of PP1 holoenzymes(2022)
Authors: Dan Wu, Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1: life-course regulation by SDS22 and Inhibitor-3(2022)
Authors: Xinyu Cao, Sarah Lemaire, Mathieu Bollen
Pages: 3072 - 3085 - Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases(2021)
Authors: Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stages(2021)
Authors: Mathieu Bollen
- Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation(2021)
Authors: Rita Derua, Monique Beullens, Mathieu Bollen
Pages: 834 - 838