Researcher
Kian Koh
- Disciplines:Developmental biology, Epigenetics, Stem cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → Today - Department of Development and Regeneration (Department)
Member
From1 Oct 2012 → 31 Mar 2013
Projects
11 - 15 of 15
- Stage-specific functions of TET proteins in somatic cell reprogramming to naive pluripotency.From1 Oct 2016 → 30 Sep 2020Funding: BOF - Concerted Research Project from 1994
- Role of hydroxymethylation as an epigenetic mark in prostate cancer biologyFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- A novel epigenetic modification in pluripotent stem cells.From1 Jan 2013 → 31 Dec 2017Funding: FWO Odysseus
- A novel epigenetic modification in pluripotent stem cells.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- A novel epigenetic modification in pluripotent stem cellsFrom1 Oct 2012 → 30 Apr 2022Funding: BOF - ZAP BOF mandates
Publications
1 - 10 of 20
- Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling(2024)
Authors: Jonathan Chui, Aneta Malesa, Paraskevi ATHANASOULI, Joris Vriens, Kian Koh, Catherine Verfaillie, Frederic Lluis Vinas
- Epigenomic, Genomic, and Environmental Interactions of TET1 in Embryonic Development(2023)
Authors: Ben van der Veer, Kian Koh
- VEGF overexpressed mesoangioblasts enhance urethral and vaginal recovery following simulated vaginal birth in rats(2023)
Authors: Marina Monteiro Carvalho Mori Da, Ben van der Veer, Laura Cattani, Kian Koh, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi, Jan Deprest
- Dual functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation(2023)
Authors: Ben van der Veer, Paraskevi ATHANASOULI, Jonathan Chui, Frederic Lluis Vinas, Kian Koh
Pages: 5469 - 5498 - The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency(2023)
Authors: Paraskevi ATHANASOULI, Ben van der Veer, Tijs Vanhessche, Kian Koh, Vincent Pasque, Catherine Verfaillie, An Zwijsen, Frederic Lluis Vinas
- Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions(2022)
Authors: Laura Yedigaryan, Ben van der Veer, Rik Gijsbers, Kian Koh, Liesbeth De Waele, Gunnar Buyse, Rita Derua, Maurilio Sampaolesi
- Wnt/beta-Catenin Inhibition Disrupts Carboplatin Resistance in Isogenic Models of Triple-Negative Breast Cancer(2021)
Authors: Stijn Moens, Ben van der Veer, Paraskevi ATHANASOULI, Emanuela Elsa Cortesi, Maria Francesca Baietti, Kian Koh, Juan-Jose Ventura, Frédéric Amant, Daniela Annibali, Frederic Lluis Vinas
- Coordination of germ-layer lineage choice by TET1 during primed pluripotency(2020)
Authors: Xinlong Luo, Ben van der Veer, Lei Sun, Michela Bartoccetti, Matteo Giovanni Maria Boretto, Hugo Vankelecom, Rita Khoueiry, Kian Koh
Pages: 598 - 618 - Regulatory dynamics of Tet1 and Oct4 resolve stages of global DNA demethylation and transcriptomic changes in the final phases of reprogramming(2020)
Authors: Michela Bartoccetti, Ben van der Veer, Xinlong Luo, Rita Khoueiry, Manmohan Bajaj, Adrian Janiszewski, Bernard Thienpont, Vincent Pasque, Kian Koh
Pages: 2150 - 2169 - Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening(2019)
Authors: Matteo Giovanni Maria Boretto, Nina Maenhoudt, Xinlong Luo, Aurélie Hennes, Bram Boeckx, Ruben Heremans, Indra Van Zundert, Hilde Brems, Benoit Cox, Marc Ferrante, et al.
Pages: 1041 - 1051