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Researcher
John Creemers
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Biochemical Neuroendocrinology (Division)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 26
- Replace a broken freeze substitution low temperature embedding system for light and electron microscopy (Leica EM AFS2)From1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- the role of Furin in colorectal cancerFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring metabolic pathways that link Congenital Myasthenic Syndrome-22, caused by PREPL deficiency to Prader-Willi SyndromeFrom19 Aug 2019 → 24 Apr 2024Funding: Foundations, funds and other with scientific goal
- PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome; functional characterization and exploration of novel therapeutic avenuesFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Therapeutic targeting of PC1/3 deficiency: from obesity to gastrointestinal disordersFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Functional characterization of PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome, and evaluation of new medication for the treatment of myastheniaFrom1 Oct 2016 → 30 Sep 2020Funding: BOF - Concerted Research Project from 1994
- Repair and upgrade of the high resolution biological SEMFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 91
- Bone-derived C-terminal FGF23 cleaved peptides increase iron availability in acute inflammation.(2023)
Authors: John Creemers
Pages: 106 - 118 - Epigenetic modulations of immune cells: from normal development to tumor progression(2023)
Authors: John Creemers
Pages: 5120 - 5144 - Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice(2022)
Authors: Ilaria Coppola, Ceyhun Alar, John Creemers
- The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance(2022)
Authors: John Creemers
- Hypergastrinemia, a clue leading to the identification of an atypical form of diabetes mellitus type 2(2022)
Authors: John Creemers
Pages: 79 - 83 - Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors(2022)
Authors: John Creemers
- The proprotein convertase furin in cancer: more than an oncogene(2022)
Authors: John Creemers
Pages: 1252 - 1262 - Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function(2021)
Authors: John Creemers
- Het ontrafelen van de rol van PREPL, een serine hydrolase gedeleteerd in een Prader-Willi-achtig syndroom(2021)
Authors: Karen Rosier, John Creemers
- In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23(2021)
Authors: John Creemers