Organisation
Laboratory for Biochemical Neuroendocrinology
Division
The Laboratory for Biochemical Neuroendocrinology conducts research into protein biosynthesis, maturation and trafficking in the (regulated) secretory pathway, in relation to human diseases like diabetes, obesity and autism.
Current researchers
1 - 3 of 3 results
- John Creemers (Responsible)
- Ilaria Coppola (Member)
- Yenthe Monnens (Member)
Projects
1 - 10 of 11
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of the proprotein convertase furin in cancerFrom22 Sep 2014 → 3 Aug 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of PREPL in regulated secretion and neuromuscular transmission.From21 Aug 2011 → 14 Sep 2014Funding: FWO fellowships
- (ATHEROGAG) Macrophage proteoglycans in atherosclerosis.From1 Jul 2011 → 15 Jun 2015Funding: Marie Curie - People
- Characterization of the regulated secretory pathway in neurons of a mouse model for autism.From1 Oct 2010 → 21 Mar 2016Funding: Private funding of national origin - undefined, FWO fellowships
- The role of furin in beta cell proliferation.From1 Aug 2009 → 19 Nov 2015Funding: IWT personal funding - strategic basic research grants
- Hyperplasia of the islets of Langerhans in transgenic mice with targeted PLAG1 overexpression in the pancreas.From1 Jan 2009 → 31 Dec 2011Funding: FWO research grant KAN
- The role of PREPL in hypotonia-cystinuria syndromeFrom8 Sep 2008 → 31 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 82
- Mutations in GTPBP3 Cause a Mitochondria! Translation Defect Associated with Hypertrophic Cardiomyopathy, Lactic Acidosis, and Encephalopathy(2014)
Authors: Luc Régal
Pages: 708 - 720 - Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1(2015)
Authors: Yanick J Crow, Diana S Chase, Johanna Lowenstein Schmidt, Marcin Szynkiewicz, Gabriella MA Forte, Hannah L Gornall, Anthony Oojageer, Beverley Anderson, Amy Pizzino, Guy Helman, et al.
Pages: 296 - 312 - TUBA1A mutations From isolated lissencephaly to familial polymicrogyria(2011)
Authors: Luc Régal
Pages: 988 - 992 - The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles(2012)
Authors: Philip Gordts, Anton Roebroek
Pages: 2198 - 2204 - PCSK1 Variants and Human Obesity(2016)
Authors: Bruno Ramos Molina
Pages: 47 - 74 - Evaluation of the pediatric patient with hypotonia: don't forget the hypotonia-cystinuria syndrome!(2012)
Authors: John Creemers, Luc Régal
Pages: 288 - Heterozygous Mutations Causing Partial Prohormone Convertase 1 Deficiency Contribute to Human Obesity(2012)
Authors: John Creemers, Pieter Stijnen
Pages: 383 - 390 - Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons(2013)
Authors: Kim Nuytens, Etienne Waelkens, Luc Régal, John Creemers
Pages: 128 - 139 - Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1(2015)
Authors: Yanick J Crow, Diana S Chase, Johanna Lowenstein Schmidt, Marcin Szynkiewicz, Gabriella M A Forte, Hannah L Gornall, Anthony Oojageer, Beverley Anderson, Amy Pizzino, Guy Helman, et al.
Pages: 296 - 312 - The role of the proprotein convertase furin in cancer(2020)
Authors: Zongsheng He, John Creemers, Sabine Tejpar