Researcher
Graciela Andrei
- Disciplines:Virology
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
11 - 15 of 15
- The rationale for repurposing cidofovir to selectively target HPV positive and negative epithelial neoplasiasFrom5 Aug 2013 → 23 Mar 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Pathogenesis and therapy of the macrophage activation syndrome in virus-induced mouse models.From1 Oct 2012 → 24 Mar 2017Funding: IWT personal funding - strategic basic research grants
- Viral infections: molecular insights, targets for intervention and drug developmentFrom1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- Herpesvirus genotyping and phenotyping to the adjustment of anitviral chemotherapy in immunocompromised cancer patients.From1 Jan 2009 → 31 Dec 2011Funding: Ministery of Social Affairs, Public Health and Environment
Publications
1 - 10 of 249
- Combination of ganciclovir and trifluridine prevents drug-resistance emergence in HSV-1.(2024)
Authors: Hanna Schalkwijk, Graciela Andrei
Pages: e0011024 - Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization(2024)
Authors: Robert Snoeck, Graciela Andrei
- A Herpes Simplex Virus 1 DNA Polymerase Multidrug Resistance Mutation Identified in a Patient With Immunodeficiency and Confirmed by Gene Editing(2023)
Authors: Hanna Schalkwijk, Graciela Andrei, Robert Snoeck
Pages: 1505 - 1515 - An observational cohort study of histological screening for BK polyomavirus nephropathy following viral replication in plasma(2023)
Authors: Evert Cleenders, Elisabet Van Loon, Katrien Lagrou, Graciela Andrei, Katrien De Vusser, Dirk Kuypers, Olga Mineeva-Sangwo, Robert Snoeck, Marc Van Ranst, Geert Verbeke, et al.
Pages: 1018 - 1034 - Synthesis of new 3-acetyl-1,3,4-oxadiazolines combined with pyrimidines as antileishmanial and antiviral agents(2023)
Authors: Johan Neyts, Dirk Jochmans, Graciela Andrei, Robert Snoeck
Pages: 2147 - 2159 - Review Article The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries(2023)
Authors: Laurens Liesenborghs, Graciela Andrei
Pages: 719 - 724 - Differences in pathogenicity among the mpox virus clades: impact on drug discovery and vaccine development(2023)
Authors: Graciela Andrei, Robert Snoeck
Pages: 719 - 739 - PRO-2000 exhibits SARS-CoV-2 antiviral activity by interfering with spike-heparin binding(2023)
Authors: Evelien Vanderlinden, Arnaud Boonen, Sam Noppen, Maya Imbrechts, Robert Snoeck, Annelies Stevaert, Lieve Naesens, Graciela Andrei, Dominique Schols
- Time-dependent variations in BK polyomavirus genome from kidney transplant recipients with persistent viremia(2023)
Authors: Olga Mineeva-Sangwo, Elisabet Van Loon, Graciela Andrei, Dirk Kuypers, Maarten Naesens, Robert Snoeck
- Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of ?-D-N4-hydroxycytidine (NHC) and a 3?-fluoro-substituted analogue of NHC(2023)
Authors: Piet Herdewyn, Robert Snoeck, Graciela Andrei
Patents
1 - 6 of 6
- Prodrugs of nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)
- Novel purine derivatives and drugs comprising same (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Prodrugs of fluorinated acyclic nucleoside phosphonates (Inventor)
- Novel prodrugs of nucleoside phosphonates (Inventor)