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Researcher
Charles De Bock
- Disciplines:Systems biology
Affiliations
- Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Nov 2012 → 31 Dec 2019
Projects
1 - 1 of 1
- Cooperation of TLX3 with epigenetic changes in the development of T-cell acute lymphoblastic leukemiaFrom1 Oct 2018 → 20 Oct 2022Funding: FWO fellowships
Publications
21 - 30 of 32
- FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation(2015)
Authors: Charles De Bock
Pages: 4653 - 4669 - Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia(2015)
Authors: Charles De Bock, Jan Cools
Pages: 2317 - 27 - T-ALL: Home Is where the CXCL12 Is(2015)
Authors: Charles De Bock, Jan Cools
Pages: 745 - 6 - ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia(2014)
Authors: Charles De Bock, Sandrine Degryse, Jan Cools
Pages: 3738 - 47 - JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model(2014)
Authors: Sandrine Degryse, Charles De Bock, Sofie Demeyer, Ellen Geerdens, Mark Fiers, Stein Aerts, Thomas Tousseyn, Jan Cools
Pages: 3092 - 3100 - FAT1 cadherin is multiply phosphorylated on its ectodomain but phosphorylation is not catalysed by the four-jointed homologue(2014)
Authors: Charles De Bock
Pages: 3511 - 3517 - Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma(2014)
Authors: Charles De Bock
- Furin processing dictates ectodomain shedding of human FAT1 cadherin(2014)
Authors: Charles De Bock
Pages: 41 - 55 - A Soluble Form of the Giant Cadherin Fat1 Is Released from Pancreatic Cancer Cells by ADAM10 Mediated Ectodomain Shedding(2014)
Authors: Charles De Bock
- Sleeping Giants: Emerging Roles for the Fat Cadherins in Health and Disease(2014)
Authors: Charles De Bock
Pages: 190 - 221