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Researcher
Bart Lesage
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → 5 Apr 2015
Projects
1 - 4 of 4
- Chaperone-guided biogenesis and activity regulation of protein phosphatase-1.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Screening for inhibitors of protein phosphatases that induce mitotic cell death in cancer cellsFrom1 Jan 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
- Chromatin signaling by protein phosphatase PP1/Repo-Man.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project
- The use of transgenice mice to unravel the in vivo functions of protein phosphatase-1.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
Publications
1 - 10 of 12
- Cdk1 orders mitotic events through coordination of a chromosome-associated phosphatase switch(2015)
Authors: Junbin Qian, Monique Beullens, Sofie De Munter, Bart Lesage, Mathieu Bollen
Pages: 10215 - Protein phosphatase PP1-NIPP1 activates mesenchymal genes in HeLa cells(2015)
Authors: Nele Van Dessel, Shannah Boens, Bart Lesage, Claudia Winkler, Aleyde Van Eynde, Mathieu Bollen
Pages: 1314 - 1321 - Aurora B defines its own chromosomal targeting by opposing the recruitment of the phosphatase scaffold repo-man(2013)
Authors: Junbin Qian, Monique Beullens, Bart Lesage, Mathieu Bollen
Pages: 1136 - 43 - The PP1 binding code: a molecular-lego strategy that governs specificity(2013)
Authors: Ewald Heroes, Bart Lesage, Janina Goernemann, Monique Beullens, Luc Van Meervelt, Mathieu Bollen
Pages: 584 - 95 - Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells(2012)
Authors: Monique Beullens, Junbin Qian, Bart Lesage, Mathieu Bollen
Pages: 10054 - 9 - Spindle Checkpoint Silencing: PP1 Tips the Balance(2011)
Authors: Bart Lesage, Junbin Qian, Mathieu Bollen
Pages: R898 - R903 - PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting(2011)
Authors: Junbin Qian, Bart Lesage, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 766 - 773 - Neural stem cells: the need for a proper orientation(2010)
Authors: Bart Lesage
Pages: 438 - 442 - Mitotic phosphatases: from entry guards to exit guides(2009)
Authors: Mathieu Bollen, Bart Lesage
Pages: 531 - 541 - Structure and Function of the Two Tandem WW Domains of the Pre-mRNA Splicing Factor FBP21 (Formin-binding Protein 21)(2009)
Authors: Monique Beullens, Emilia Nicolaescu, Bart Lesage, Mathieu Bollen
Pages: 25375 - 25387