Researcher
Barbara De Moerloose
- Keywords:acute myeloid leukemia, juvenile myelomonocytic leukemia, CART treatment, bone marrow failure, myelodysplasia, acute lymfoblastic leukemia
- Disciplines:Paediatrics and neonatology, Cancer therapy, Hematology, Cancer biology, Cancer diagnosis
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 1994 → 30 Sep 2018
Projects
1 - 5 of 5
- Research assignment of Prof. dr. Tim Lammens, framing the ongoing clinical-translational research at the Department of Pediatric Hematology-Oncology and Stem Cell TransplantationFrom1 Oct 2023 → TodayFunding: Nonprofit institution or equivalents
- Integration of genome, epigenome, and transcriptome in juvenile myelomonocytic leukemia and functional analysis of circular RNAs as novel biomarker and/or therapeutic targetsFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Preclinical evaluation of newly identified therapeutic targets in pediatric acute myeloid leukemiaFrom1 Oct 2021 → TodayFunding: Nonprofit institution or equivalents
- Long non-coding RNAs as therapeutic targets in acute myeloid leukemiaFrom1 Oct 2020 → 30 Sep 2021Funding: Nonprofit institution or equivalents
- Evaluation of the prognostic value of the leukemic stem cell (LSC) and pre-leukemic hematopoietic stem cell (pre-L HSC) for minimal residual disease monitoring and clinical management of pediatric acute myeloid leukemia patientsFrom1 Jan 2015 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
Publications
21 - 30 of 137
- Germline SAMD9L triple-allelic mosaicism with independent segregation into biallelic offsprings : molecular support for non-mendelian inheritance(2021)Volume: 8
Authors: S Sahoo, C Goodings, M Angeles Lillo, Tim Lammens, J van der Werff ten Bosch, B Strahm, Barbara De Moerloose, M Wlodarski
Number of pages: 1 - Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes(2021)
Authors: Sushree S. Sahoo, Victor B. Pastor, Charnise Goodings, Rebecca K. Voss, Emilia J. Kozyra, Amina Szvetnik, Peter Noellke, Michael Dworzak, Jan Stary, Franco Locatelli, et al.
Pages: 1806 - 1817 - Features and outcome of chronic myeloid leukemia at very young age : data from the International Pediatric Chronic Myeloid Leukemia Registry(2021)
Authors: Adalet Meral Gunes, Frederic Millot, Krzysztof Kalwak, Birgitte Lausen, Petr Sedlacek, A. Birgitta Versluys, Michael Dworzak, Barbara De Moerloose, Meinolf Suttorp
- The variable biological signature of refractory cytopenia of childhood (RCC), a retrospective EWOG-MDS study(2021)
Authors: Demi T.C. de Winter, Anton W. Langerak, Jeroen te Marvelde, Michael N. Dworzak, Barbara De Moerloose, Jan Starý, Franco Locatelli, Henrik Hasle, Andrica C.H. de Vries, Markus Schmugge, et al.
- A semi-mechanistic population pharmacokinetic/pharmacodynamic model of bortezomib in pediatric patients with relapsed/refractory acute lymphoblastic leukemia(2020)
Authors: Julie M Janssen, TPC Dorlo, D Niewerth, AJ Wilhelm, CM Zwaan, JH Beijnen, A Attarbaschi, A Baruchel, F Fagioli, T Klingebiel, et al.
Pages: 207 - 216 - Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency(2020)
Authors: Emilia J. Kozyra, Victor B. Pastor, Stylianos Lefkopoulos, Sushree S. Sahoo, Hauke Busch, Rebecca K. Voss, Miriam Erlacher, Dirk Lebrecht, Enikoe A. Szvetnik, Shinsuke Hirabayashi, et al.
Pages: 2673 - 2687 - Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma(2020)
Authors: Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Béatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, et al.
Pages: 1685 - 1695 - Not all pediatric intestinal polyps are alike(2020)
Authors: Drieke Vermeulen, Myriam Van Winckel, Saskia Vande Velde, Ruth De Bruyne, Stephanie Van Biervliet, Barbara De Moerloose, LUCAS MATTHYSSENS, Dirk Van de Putte
Pages: 393 - 397 - Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib : a report from the I-CML-Ped Study(2020)
Authors: Deborah Meyran, Arnaud Petit, Joelle Guilhot, Meinolf Suttorp, Petr Sedlacek, Eveline De Bont, Chi Kong Li, Krzysztof Kalwak, Brigitte Lausen, Srdjana Culic, et al.
Pages: 224 - 234 - The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing(2020)
Authors: L Zubovic, S Piazza, T Tebaldi, L Cozzuto, G Palazzo, V Sidarovich, V De Sanctis, R Bertorelli, Tim Lammens, Mattias Hofmans, et al.