Researcher
Aleyde Van Eynde
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
11 - 17 of 17
- Exploration of the therapeutic potential of protein phosphatases involved in chromatin signaling.From1 Oct 2009 → 30 Sep 2014Funding: BOF - Concerted Research Project from 1994
- Implementation of functional imaging and molecular diagnostics for patient-tailored treatment of prostate cancer.From15 Sep 2009 → 30 Jun 2015Funding: Ministery of Social Affairs, Public Health and Environment
- Epigenetic control by the proliferation regulator NIPP1.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project
- PolycombGroup targets as DNA methylation biomarkers for improved diagnosis, prognosis and predictor as response to treatment of prostate cancer.From1 Jan 2009 → 30 Sep 2015Funding: Ministery of Social Affairs, Public Health and Environment
- Genome-wide promotor binding profiling of Protein phosphatase 1 and its major nuclear targeting subunitsFrom1 Oct 2008 → 30 Sep 2014Funding: BOF - Doctoral projects
- IOF-HB/07/049.From1 Jun 2008 → 1 Jul 2009Funding: Own budget, for example: patrimony, inscription fees, gifts
- Genome-wide exploration of the protein phosphatase-1 interactome.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
Publications
1 - 10 of 42
- Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice.(2024)
Authors: Marloes Jonkhout, Tijs Vanhessche, Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: S0022-202X - DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1(2024)
Authors: Aleyde Van Eynde, Mathieu Bollen
- Substrate mapping and activity regulation of PP1 holoenzymes(2022)
Authors: Dan Wu, Mathieu Bollen, Aleyde Van Eynde
- Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases(2021)
Authors: Mathieu Bollen, Aleyde Van Eynde
- Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1(2020)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
- The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation.(2020)
Authors: Iris Verbinnen, Marloes Jonkhout, Kathelijne Szekér, Margareta Nikolic, Susan Schlenner, Aleyde Van Eynde, Mathieu Bollen
Pages: 1576 - 1588 - The phosphatase regulator NIPP1 restrains chemokine-driven inflammation and DNA-damage repair in the skin(2019)
Authors: Iris Verbinnen, Mathieu Bollen, Aleyde Van Eynde
- Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.(2019)
Authors: Monique Beullens, Mathieu Bollen, Aleyde Van Eynde
Pages: 16 - 30 - MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells (vol 35, e00267, 2015)(2018)
Authors: Lijs Beke, Cenk Kig, Joannes TM Linders, Shannah Boens, An Boeckx, Erika van Heerde, Marc Parade, An De Bondt, Ilse Van den Wyngaert, Tarig Bashir, et al.
- The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2(2018)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: 18031 - 18039