Development of a comprehensive methodology predicting human Norovirus infectivity and study of the interaction between human Norovirus and different microbial environments

This study inculdes two parts: I. An extension study on the binding-based methodologies: to establish a methodology predicting the infectivity of NoV by evaluating both viral capsid function and genome integrity; II. Exploration of the interaction between NoV and certain microbial environments, including the human digestive environment and the microbial environment during biological treatments.