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Researcher
Jorick Franceus
- Keywords:protein evolution, biocatalysis
- Disciplines:Molecular evolution, Industrial molecular engineering of nucleic acids and proteins, Biocatalysis and enzyme technology, Proteins
Affiliations
- Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Biochemical and microbial technology (Department)
Member
From1 Oct 2014 → 31 Dec 2017
Projects
1 - 3 of 3
- Off the beaten path of protein evolution: insertions and deletions as drivers of functional innovationFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Retracing the steps of enzyme evolution: an exploration of ancestral sequence spaceFrom1 Oct 2020 → 30 Sep 2023Funding: FWO junior postdoctoral fellowship
- Redirected evolution as strategy for the development of new enzymes.From1 Jan 2016 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 24
- High-yield synthesis of 2-O-α-d-glucosyl-d-glycerate by a bifunctional glycoside phosphorylase(2024)
Authors: Jorick Franceus, Manon Steynen, Yentl Allaert, Kato Bredael, Matthias D'hooghe, Tom Desmet
- Insertions and deletions in protein evolution and engineering(2022)
Authors: Simone Savino, Jorick Franceus
- Building mutational bridges between carbohydrate-active enzymes(2022)
Authors: Jorick Franceus, Jolien Lormans
- Identification of mercaptoacetamide-based HDAC6 inhibitors via a lean inhibitor strategy : screening, synthesis, and biological evaluation(2022)
Authors: Freya Baele, Jorick Franceus, Matthias D'hooghe
Pages: 6239 - 6242 - Discovery of a kojibiose hydrolase by analysis of specificity-determining correlated positions in Glycoside Hydrolase Family 65(2021)
Authors: Emma De Beul, Jorick Franceus, Tom Desmet
- Engineering of a thermostable biocatalyst for the synthesis of 2-O-glucosylglycerol(2021)
Authors: Jorick Franceus, Zorica Ubiparip, Koen Beerens, Tom Desmet
Pages: 2777 - 2782 - Exploration of GH94 sequence space for enzyme discovery reveals a novel glucosylgalactose phosphorylase specificity(2021)
Authors: Marc De Doncker, Chloé De Graeve, Jorick Franceus, Koen Beerens, Vladimír Kren, Helena Pelantová, Ronny Vercauteren
Pages: 3319 - 3325 - Evolution of phosphorylases from N-acetylglucosaminide hydrolases in family GH3(2021)
Authors: Jorick Franceus, Jolien Lormans, Lore Cools, Matthias D'hooghe
Pages: 6225 - 6233 - β-Glucan phosphorylases in carbohydrate synthesis(2021)
Authors: Zorica Ubiparip, Marc De Doncker, Jorick Franceus
Pages: 4073 - 4087 - Synthesis, trehalase hydrolytic resistance and inhibition properties of 4-and 6-substituted trehalose derivatives(2020)
Authors: Johan Van der Eycken, Jorick Franceus, Jurgen Caroen
Pages: 1964 - 1989