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Researcher
Silvia Jansen
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → 30 Sep 2013
Projects
1 - 2 of 2
- NPP1 as a potential therapeutic target for mineralization disorders.From1 Jan 2012 → 31 Dec 2014Funding: FWO research grant KAN
- Exploration of the ectophosphodiesterase NPP1 as a target for the treatment of calcification diseases.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
1 - 6 of 6
- Structure of NPP1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification(2012)
Authors: Silvia Jansen, Chris Ulens, Claudia Winkler, Maria Andries, Frank Luyten, Mathieu Bollen
Pages: 1948 - 1959 - Structural basis of substrate discrimination and integrin binding by autotaxin(2011)
Authors: Silvia Jansen, Maria Andries, Mathieu Bollen
Pages: 198 - 204 - Expression of lyosophospholipase D/autotaxin by breast cancer cells controls bone metastasis formation by increasing osteoclast differentiation(2010)
Authors: Marion David, Estelle Wannecq, Silvia Jansen, Blandine Deux, Johnny Ribeiro, Claire-Marie Serre, Sandra Gres, Nathalie Bendriss-Vermare, Mathieu Bollen, Jean-Sebastien Saulnier-Blache, et al.
Pages: S41 - S41 - Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells(2009)
Authors: Silvia Jansen, Maria Andries, Katrien Vekemans, Alfons Verbruggen, Mathieu Bollen
Pages: 216 - 21 - Domain Interplay Mediated by an Essential Disulfide Linkage Is Critical for the Activity and Secretion of the Metastasis-promoting Enzyme Autotaxin(2009)
Authors: Silvia Jansen, Maria Andries, Rita Derua, Etienne Waelkens, Mathieu Bollen
Pages: 14296 - 14302 - Cancer Cell Expression of Autotaxin Controls Bone Metastasis Formation in Mouse through Lysophosphatidic Acid-Dependent Activation of Osteoclasts
Authors: Silvia Jansen, Mathieu Bollen