The overall aim of the research of the Laboratory of Translational Genetics, is to unravel the genetic predisposition to cancer and to annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies.
The research group Reproduction and Genetics (REGE) is part of the research cluster Reproduction Genetics and Regenerative Medicine. Its research focuses on different aspects of human genetics, reproduction, early development and stem cells
Historically, the group has been interested in metabolic diseases such as lysosomal storage diseases and this has led to the close collaboration of S. Seneca with the ...
Research topics of this unit are:
• Bacteria-plant interactions
• Symbiosis between Rhizobium etli and Phaseolus vulgaris
• Symbiotic nitrogen fixation
• Quorum sensing and biofilm formation in Rhizobium
• Bacterial physiology: the stringent response in Rhizobium
• Type III protein secretion in Rhizobium
• Calcium-binding proteins in bacteria
• Mechanisms of antibiotic resistance and tolerance in ...
Research in the Laboratory of Plant Genetics concerns basic plant molecular genetics as well as applied research relevant to the plant biotechnology and agricultural sector. The research is focused on the following themes: · DNA repair and recombination mechanisms and methods to influence these processes. This may lead to development of improved plant breeding techniques, improved plant transformation technology and new techniques for ...
The core business of REGE is the interphase between reproduction and genetics, a wide discipline covering several subdisciplines. Male infertility and the search for genes involved in spermatogenensis is a first topic that is mainly investigated within the Centre for Medical Genetics. A second important topic covers the (epi)genetics of embryos and embryonic stem cells, amongst others the investigation of chromosomal abnormalities, epigenetic ...