Our research group is interested in human evolution and evolutionary population genetics in the broadest sense. We work on questions relating global genetic population structure with evolutionary processes such as selection, drift, migrations and admixture. We use evidence from modern and ancient genomes to study genetic changes taking place over time and space.
The research group Reproduction and Genetics (REGE) is part of the research cluster Reproduction Genetics and Regenerative Medicine. Its research focuses on different aspects of human genetics, reproduction, early development and stem cells
Historically, the group has been interested in metabolic diseases such as lysosomal storage diseases and this has led to the close collaboration of S. Seneca with the ...
Research in the Laboratory for Genetics of Cognition focuses on the clinical, genetic and molecular characterization of genetic disorders, associated with intellectual disability, X-linked as well as autosmal. Besides gene identification, applying the latest technology, we are also involved in developing models for neurodevelopmental disorders using the induced pluripotent stem cell technology.
The overall aim of the research of the Laboratory of Translational Genetics, is to unravel the genetic predisposition to cancer and to annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies.
In this research area, we survey the genetic diversity, habitat and evolution over time of plant populations. Relationships between and among genetic sources are applied to breeding. This breeding research includes development and use of molecular markers, embryo rescue, polyploidization and protoplast fusion. We make (interspecific) crosses with improved disease resistance, better use of nutrients, drought resistance, and more.