Projects
Xenotransplantation of iPSC-derived microglia to elucidate the impact of C9orf72 hexanucleotide repeat expansion on neuroinflammation and neurodegeneration. University of Antwerp
Xenotransplantation of iPSC derived microglia to decipher the impact of Progranulin in neuroinflammation and neurodegeneration. University of Antwerp
Xenotransplantation of genetically engineered iPSC-derived microglia and neurons to decipher the cell-type specific interplay of Progranulin and TMEM106B in neuroinflammation and neurodegeneration. University of Antwerp
in vivo model for MECP2 - related diseases using iPSC and xenotransplantation KU Leuven
Given the uniqueness of the human brain and the difficulty to study the brain of patients at the cellular and molecular levels (neuronal material/brain biopsy), the advent of human pluripotent stem cell (PSC) has offered new opportunities to study human neural development in health and disease. We apply since 2014 the iPSC technology, to model neurodevelopmental disorders in vitro, such as MECP2 duplication syndrome and Rett syndrome. In this ...
Designed for Communion but Devalued by Commodification: An Analysis of the Moral Status of Animals in Roman Catholic Theology after Laudato Si’ and its Implications for the Ethical Evaluation of Genetically Modified Animals for Xenotransplantation KU Leuven
The Catholic Church has developed a consistent moral response to ecological issues. However, the moral status of animals within the framework of Catholic ecological theology is a neglected and unexplored area until and even after the publication of Laudato Si. The encyclical strongly affirmed and recognized the natural world but does not say much about animals. Taking this as the point of departure, this project with an ...