Publications
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in Type 1 diabetic patients. Vrije Universiteit Brussel
Lymphocyte pharmacodynamics are not associated with autoimmunity or efficacy after alemtuzumab Hasselt University
WHO multicenter evaluation of FACSCount CD4 and Pima CD4 T-cell count systems Institute of Tropical Medicine University of Antwerp
BACKGROUND: CD4⁺ T-cell counts are used to screen and follow-up HIV-infected patients during treatment. As part of the World Health Organization prequalification program of diagnostics, we conducted an independent multicenter evaluation of the FACSCount CD4 and the Pima CD4, using the FACSCalibur as reference method.
METHODS: A total of 440 paired capillary and venous blood samples were collected from HIV-infected patients attending ...
Long-term residential exposure to air pollution is associated with hair cortisol concentration and differential leucocyte count in Flemish adolescent boys Ghent University KU Leuven Vrije Universiteit Brussel University of Antwerp Hasselt University
Study of the association of total and differential white blood cell counts with geriatric conditions, cardio-vascular diseases, seric IL-6 levels and telomere length Vrije Universiteit Brussel
BACKGROUND/OBJECTIVES: Geriatric patients are highly susceptible to infections. While reduced lymphocyte count has been associated with age, other studies found no change in WBC counts with age. Increased circulating white blood cell (WBC) count has been associated with cardiovascular (CV) diseases and frailty but there are discrepancies. Frailty, geriatric conditions, cardiovascular diseases and WBC count have also been associated with low ...
Computed CD4 percentage as a low-cost method for determining pediatric antiretroviral treatment eligibility Institute of Tropical Medicine University of Antwerp Ghent University
The role of non-viral load surrogate markers in HIV-positive patient monitoring during antiviral treatment Institute of Tropical Medicine
Simplified clinical prediction scores to target viral load testing in adults with suspected first line treatment failure in Phnom Penh, Cambodia Institute of Tropical Medicine
BACKGROUND: For settings with limited laboratory capacity, 2013 World Health Organization (WHO) guidelines recommend targeted HIV-1 viral load (VL) testing to identify virological failure. We previously developed and validated a clinical prediction score (CPS) for targeted VL testing, relying on clinical, adherence and laboratory data. While outperforming the WHO failure criteria, it required substantial calculation and review of all previous ...