Context-aware identification of kinase-substrate association and protein phosphorylation through large scale proteomics experiment reprocessing. Ghent University
Protein function is highly regulated by the co-ordinated expression and interaction in different tissues and the correct localization within different sub-cellular compartments. A common mechanism for protein regulation are post-translational modifications (PTMs). Protein phosphorylation is the most prevalent and well-studied PTM in eukaryotes, with involvement in diseases such as cancer and Alzheimer’s. This reversible modification is ...