Publications
Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis Vrije Universiteit Brussel
Transcription factor Growth Factor Independence 1 (GFI1) regulates the expression of genes important for survival, proliferation and differentiation of hematopoietic cells. A single nucleotide polymorphism (SNP) variant of GFI1 (GFI1-36N: serine replaced by asparagine at position 36), has a prevalence of 5-7% among healthy Caucasians and 10-15% in patients with myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML) predisposing ...
Incidence, Risk Factors, and Prognosis of Intra-Abdominal Hypertension in Critically Ill Children Vrije Universiteit Brussel
PURPOSE: To assess the incidence, risk factors, and outcomes of intra-abdominal hypertension (IAH) in a pediatric intensive care unit (PICU).
METHODS: Prospective cohort study from January 2011 to January 2013. All children consecutively admitted to the PICU, staying more than 24 hours and requiring bladder catheterization, were included in the study. On admission, demographic data and risk factors for IAH were studied. The ...
Incidence and prognosis of intra-abdominal hypertension and abdominal compartment syndrome in severely burned patients Vrije Universiteit Brussel
BACKGROUND: Burn patients are at high risk for secondary intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) due to capillary leak and large volume fluid resuscitation. Our objective was to examine the incidence the incidence of IAH and ACS and their relation to outcome in mechanically ventilated (MV) burn patients.
METHODS: This observational study included all MV burn patients admitted between April 2007 and ...