Publications
Rapid detection of Mycobacterium tuberculosis strains resistant to isoniazid and/or rifampicin: standardization of multiplex polymerase chain reaction analysis Institute of Tropical Medicine University of Antwerp
Drug susceptibility testing using molecular techniques can enhance the identification of drug-resistant Mycobacterium tuberculosis. Two multiplex real-time polymerase chain reaction (qPCR) assays were developed to detect the most common resistance-associated mutations to isoniazid (katGS315T, inhA-15C -> T), and rifampicin (rpoBH526Y and rpoBS531L). To assess the species specificity of the qPCR, we selected 31 nontuberculous mycobacteria ...
Analysis of Liver Connexin Expression Using Reverse Transcription Quantitative Real-Time Polymerase Chain Reaction Vrije Universiteit Brussel
An integrated one-chip-sensor system for microRNA quantitative analysis based on digital droplet polymerase chain reaction KU Leuven
Development, evaluation, and integration of a quantitative reverse-transcription polymerase chain reaction diagnostic test for Ebola virus on a molecular diagnostics platform University of Antwerp Institute of Tropical Medicine
Utility of Microscopic Techniques and Quantitative Real-time Polymerase Chain Reaction for the Diagnosis of Vaginal Microflora Alterations KU Leuven University of Antwerp
Validation of an apicoplast genome target for the detection of Plasmodium species using polymerase chain reaction and loop mediated isothermal amplification Institute of Tropical Medicine KU Leuven University of Antwerp
The genome of the Plasmodium apicoplast, which has a higher copy number compared with current targets for molecular diagnosis of malaria, appears to be a suitable target for detection of submicroscopic infections that are capable of sustaining transmission. Novel primers targeting a conserved segment of the apicoplast (PFC10_AP|0010:rRNA) were designed and used in a number of different high throughput platforms such as single-step PCR ...