Publications
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The metabolic blueprint of Phaeodactylum tricornutum reveals a eukaryotic Entner-Doudoroff glycolytic pathway Ghent University
Identification and functional characterization of cell cycle genes in the pennate diatom Phaeodactylum tricornutum Ghent University
Flux balance analysis of primary metabolism in the diatom Phaeodactylum tricornutum KU Leuven Ghent University
Diatoms (Bacillarophyceae) are photosynthetic unicellular microalgae that have risen to ecological prominence in oceans over the past 30 million years. They are of interest as potential feedstocks for sustainable biofuels. Maximizing production of these feedstocks will require genetic modifications and an understanding of algal metabolism. These processes may benefit from genome-scale models, which predict intracellular fluxes and theoretical ...
The multifaceted inhibitory effects of an Alkylquinolone on the Diatom Phaeodactylum tricornutum University of Antwerp Ghent University
The mechanisms underlying interactions between diatoms and bacteria are crucial to understand diatom behaviour and proliferation, and can result in far-reaching ecological consequences. Recently, 2-alkyl-4-quinolones have been isolated from marine bacteria, both of which (the bacterium and isolated chemical) inhibited growth of microalgae, suggesting these compounds could mediate diatom–bacteria interactions. The effects of several quinolones on ...
Impact of harvesting method on total lipid content and extraction efficiency for Phaeodactylum tricornutum KU Leuven
Flocculation is a promising low-cost alternative to centrifugation for harvesting microalgae for bulk lipid production. However, little is known about the effect of the harvesting method on the lipid content on the one hand and the lipid extraction efficiency on the other hand. In this study, both total lipid content (and fatty acid composition and free fatty acid amount) and lipid extraction efficiency of Phaeodactylum tricornutum biomass were ...
The transcription factor bZIP14 regulates the TCA cycle in the diatom Phaeodactylum tricornutum Flanders Institute for Biotechnology KU Leuven Ghent University
Influence of Drying and Storage on Lipid and Carotenoid Stability of the Microalga Phaeodactylum tricornutum KU Leuven Ghent University
The influence of short-term storage and spray- and freeze-drying of fresh microalgal paste on the stability of lipids and carotenoids of Phaeodactylum tricornutum was investigated. Furthermore, the effects of storage time (14 and 35 days) and condition (vacuum packed vs non vacuum packed, 20 degrees C vs 4 degrees C vs 20 degrees C) after spray- and freeze-drying were studied. Total lipid content, free fatty acid content, carotenoid content and ...
Alkaline flocculation of Phaeodactylum tricornutum induced by brucite and calcite KU Leuven
Alkaline flocculation holds great potential as a low-cost harvesting method for marine microalgae biomass production. Alkaline flocculation is induced by an increase in pH and is related to precipitation of calcium and magnesium salts. In this study, we used the diatom Phaeodactylum tricornutum as model organism to study alkaline flocculation of marine microalgae cultured in seawater medium. Flocculation started when pH was increased to 10 and ...