Publications
Chosen filters:
Chosen filters:
Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism KU Leuven
Chronic thromboembolic pulmonary hypertension (CTEPH) is the most severe long-term complication of acute pulmonary embolism (PE). Untreated CTEPH is fatal, but, if diagnosed in time, successful surgical (pulmonary endarterectomy), medical (pulmonary hypertension drugs) and/or interventional (balloon pulmonary angioplasty) therapies have been shown to improve clinical outcomes, especially in case of successful pulmonary endarterectomy. Early ...
PULMONARY REHABILITATION IN EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A PERSON-CENTRED RESEARCH Hasselt University
Symptomen, functionele status en exacerbaties zijn belangrijke problemen van mensen met chronisch obstructief longlijden (COPD) en dragen in hoge mate bij aan de ziektelast; toch worden deze problemen nog steeds niet volledig begrepen. Het verder begrijpen van de symptomen, de functionele status en het beloop van exacerbaties van COPD (ECOPD), evenals het identificeren van strategieën om de last ervan te minimaliseren, zijn daarom erkende ...
Right Heart Failure in a Patient with Critical Pulmonary Stenosis, Absent Right Pulmonary Artery, and Lung Cancer KU Leuven
BACKGROUND Unilateral absence of a pulmonary artery (UAPA) is a rare congenital cardiovascular malformation. More than half of UAPA cases have other cardiac lesions such as tetralogy of Fallot or septal defects. Clinical manifestations are diverse and range from heart failure after birth to an incidental finding on chest imaging during adulthood. Whereas early surgical revascularization is recommended in infancy, this is usually not feasible in ...
The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution Ghent University Flanders Institute for Biotechnology University of Antwerp KU Leuven Institute of Tropical Medicine
Aims Severe acute respiratory syndrome coronavirus-2 infection causes COVID-19, which in severe cases evokes life-threatening acute respiratory distress syndrome (ARDS). Transcriptome signatures and the functional relevance of non-vascular cell types (e.g. immune and epithelial cells) in COVID-19 are becoming increasingly evident. However, despite its known contribution to vascular inflammation, recruitment/invasion of immune cells, vascular ...
Pulmonary toxicity of nanoparticles, influence on the barrier of the pulmonary epithelium KU Leuven
mso-ansi-language:EN-US" lang="EN-US">Nanotechnology is already being used in severalindustries for a very diverse range of products: personal care products,cosmetics, sunscreens, clothing, sporting goods, electronics, food and beverages,paints and coatings. The production of nanoparticles and their marketing willincrease even more in the coming years.mso-ansi-language:EN-US" lang="EN-US">It is generally assumed that the physical and ...
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease KU Leuven
BACKGROUND: Pulmonary rehabilitation has become a cornerstone in the management of patients with stable Chronic Obstructive Pulmonary Disease (COPD). Systematic reviews have shown large and important clinical effects of pulmonary rehabilitation in these patients. In unstable COPD patients who have suffered from an exacerbation recently, however, the effects of pulmonary rehabilitation are less established. OBJECTIVES: To assess the effects of ...
Update on pulmonary ossifications in the differential diagnosis of solitary pulmonary nodules University of Antwerp
Pulmonary ossifications have often been regarded as rare, post-mortem findings without any clinical significance. We have investigated the occurrence of pulmonary ossifications in patients undergoing thoracic procedures, and how this may affect the differential diagnosis of solitary pulmonary nodules. In addition, we have performed a literature search on the occurrence and possible pathogenesis of these ossifications. From January 2008 until ...
Role of inflammation in pulmonary vascular cell dysfunction in pulmonary arterial hypertension KU Leuven
Title: Role of inflammation in pulmonary vascular cell dysfunction in pulmonary arterial hypertension Summary Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by an arteriopathy of the pre-capillary pulmonary arteries. Heritable pulmonary arterial hypertension is associated with mutations in the bone morphogenetic protein receptor 2 (BMPR2) gene. However, only 20% of BMPR2 mutation carriers develop PAH. ...
External validation of the Ferguson pulmonary risk score for predicting major pulmonary complications after oesophagectomy KU Leuven
OBJECTIVES: Pulmonary complications remain a frequent cause of morbidity in patients undergoing oesophagectomy. Risk screening tools assist in patient stratification. Ferguson proposed a risk score system to predict major pulmonary complications after oesophagectomy. Our objective was to externally validate this risk score system. METHODS: We analysed our institutional database for patients undergoing oesophagectomy for cancer from August 2009 ...