Projects
The FiREwORK trial - self-management with FootweaR combined with Exercise for OsteoaRthritis (OA) at the Knee: a phase II randomized controlled trial Ghent University
Knee OA is an important cause of disability worldwide. No effective cure exists and many patients
will eventually undergo costly joint replacement. Clinical guidelines emphasize that non-drug nonsurgical
treatment should constitute first-line treatment. Exercise therapy is strongly recommended
for knee OA. However, overall treatment effects on symptoms are modest at best, which is further
...
Preservation and repair of the joint: meeting the osteoarthritis challenge Ghent University
Osteoarthritis is the most common chronic joint disease for which no cure or specific treatment is available. The cartilage is the tissue that caps the bones and that allows soft movement in the joint. In osteoarthritis, the cartilage and the joint are damaged. This project
will focus on strategies to maintain the health of the cartilage and the other tissues of the joint and to repair the joint when it is damaged. The research team ...
Preservation and repair of the joint: meeting the osteoarthritis challenge KU Leuven
Osteoarthritis is the most common chronic joint disease for which no cure or specific treatment is available. The cartilage is the tissue that caps the bones and that allows soft movement in the joint. In osteoarthritis, the cartilage and the joint are damaged. This project will focus on strategies to maintain the health of the cartilage and the other tissues of the joint and to repair the joint when it is damaged. The research team brings ...
Advanced personalised, multi-scale computer models preventing OsteoArthritis KU Leuven
Osteoarthritis (OA) is a degenerative disease of the articular cartilage and the most common form of arthritis that causes joint pain, mobility limitation and, thus, reduces independence and overall quality of life. Although the usual population associated with the condition is the elderly (65 years old ranges from 12- 30%), who are mostly inactive, athletes and younger individuals are also susceptible. Whilst the available data have ...
Mechanical and Structural Alterations after Surgical Treatment of Wrist Osteoarthritis KU Leuven
Wrist osteoarthritis (OA) is one of the most common conditions encountered by hand surgeons. There is no cure to OA. In severe cases, surgical treatment, such as proximal row carpectomy or four corner arthrodesis is performed to reduce pain and to improve mobility; yet, with varying success rates and controversy exists on which procedure is the optimal one. It is hypothesized that patient-specific differences in bone microstructure play a ...
PINPOINT - clinical Phenotypes of the INfraPatellar fat pad and Optimized Interventions for kNee osTeoarthritis Ghent University
PINPOINT aims to underpin clinical (i.e., biomechanical and/or inflammatory) subtypes of the infra-patellar fat pad, their role in the onset and progression of knee osteoarthritis (OA)and implications
for the design of optimised and targeted multi-modal interventions of knee OA.
Controlling Cartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis KU Leuven
A well-functioning locomotor system is essential for human well-being. This is an important consideration in our aging population with the increased associated costs of ensuring high quality of life. Many people suffer from diseases of the locomotor system, such as bone defects or osteoarthritis, for which current treatments are insufficient. To develop new treatments, CarBon includes 6 academic partners, 3 companies and 3 charitable ...
Researching an evidence-based orthosis design for the treatment of osteoarthritis of the thumb KU Leuven
Osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of articular cartilage which leads to joint pain and decrease in mobility. OA is caused by multiple factors, a combination of systemic susceptibility (metabolism, a hereditary predisposition and hormonal imbalances) and mechanical factors such as bone geometry, muscle weakness and ligament laxity. This can lead to a misalignment of articular surfaces which ...