Identifying the functional outcome of different antigen presenting cells for NKT cell activation in the liver. Ghent University
NKT cells are a unique immune cell type that show great promise in cancer immunotherapy.
However, clinical application is hampered by both the production of cytokines with opposing effects
on the immune system and the induction of anergy, a hyporesponsiveness that prevents repeated
activation of NKT cells. There is evidence suggesting that these limitations are related to the nature
of the antigen presenting cell that ...