Laboratory for Molecular Neurobiomarker Research KU Leuven
Laboratory of Molecular Neuro Biomarker Research
Laboratory of Molecular Neuro Biomarker Research
The laboratory for Molecular Digestive Oncology focusses on gastro-intestinal cancers and currently has two types of activities:
Tomographic evaluation of tracer distribution (PET, SPECT). - Medical Imaging: acquition, reconstruction PET and SPECT. - Metabolic Imaging in acute and chronic heart disease. - Metabolic Imaging in oncology and inflammation - Neuroactivation, protein deposit and receptor studies of the brain. - Radio immunotherapy. - Molecular imaging - Brain imaging. - Image registration (PET, SPECT, MRI, CT).
The translational research activities of the diagnostic team concern the development and validation of new technologies for use in diagnostics. The lab has developed specific gene panels for various genetically heterogeneous disorders and offers 'mendelioom' sequencing within the clinical service.
The In Vivo Cellular and Molecular Imaging (ICMI) Core Facility is specialized in nuclear and optical imaging of small animals. The lab is equipped with a myriad of multi-modality cameras and ex vivo analysis techniques to study tracer biodistribution, pharmacokinetics, dosimetry, and therapeutic efficacy of radiopharmaceuticals. The lab is situated in a biosafety level 2 environment with direct access to the animalarium.
This unit operates in close association with the Division of Immunolbiology (A. Billiau). Together these teams investigate the immunobiology of inflammation, auto-immunity and cancer, with emphasis on the role of cytokines (interferons, interleukins, cytotoxins and chemokines) and cellular proteases (plasminigen activators, collgenases, etc.). Projects and milestones in this framework comprise: - Identification in molecular and biological ...