Publications
Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS Institute of Tropical Medicine University of Antwerp
BACKGROUND: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral therapy (ART). TB-IRIS could be associated with an exaggerated immune response to TB-antigens. We compared the recovery of IFNγ responses to recall and TB-antigens and explored in vitro innate cytokine production in TB-IRIS patients.
METHODS: In a prospective ...
The use of Interferon-gamma release assays for tuberculosis screening in international travelers Institute of Tropical Medicine
Interferon-gamma release assay (Modified QuantiFERON) as a potential marker of infection for Leishmania donovani, a proof of concept study Institute of Tropical Medicine
Human and rodent interferon-gamma as a growth factor for Trypanosoma brucei Institute of Tropical Medicine
Tuberculin skin test versus interferon-gamma release assays for the diagnosis of tuberculosis infection Ghent University
Crucial role of interferon-gamma in experimental autoimmune prostatitis KU Leuven
Interferon-gamma en 'natural killer' cellen in systemische juveniele idiopathische artritis en macrofaagactivatiesyndroom KU Leuven
Interferon-gamma expression and infectivity of Toxoplasma infected tissues in experimentally infected sheep in comparison with pigs Institute of Tropical Medicine Ghent University KU Leuven
Livestock animals are a potential risk for transmission of toxoplasmosis to humans. Sheep and pigs still remain an important source because their meat is often eaten undercooked which has been regarded as a major route of infection in many countries. Moreover, porcine tissues are processed in many food products. In the current study, the IFN-gamma (T-helper 1 cells), IL-4 (Th2 cells) and IL-10 mRNA (Treg cells) expression by blood mononuclear ...
Strain- and dose-dependent reduction of burden in pigs is associated with interferon-gamma production by CD8 lymphocytes in a heterologous challenge model Institute of Tropical Medicine Ghent University
Toxoplasma gondii is a worldwide prevalent parasite of humans and animals. The global infection burden exceeds yearly one million disability-adjusted life years (DALY's) in infected individuals. Therefore, effective preventive measures should be taken to decrease the risk of infection in humans. Although human toxoplasmosis is predominantly foodborne by ingestion of tissue cysts in meat from domestic animals such as pigs, the incidence risk ...