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Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma Ghent University University of Antwerp
Purpose: Gemcitabine is a promising adjuvant treatment for patients with resected pancreatic adenocarcinoma and its use in combination with radiotherapy is under exploration. Human equilibrative nucleoside transporter 1 (hENT1) and human concentrative nucleoside transporter (hCNT) 1 and 3 are the major transporters responsible for 2',2'-difluoro-2-deoxycytidine (gemcitabine) uptake into cells. The aim of this study was to determine patients' ...
A phase Ib/IIa trial to evaluate the CCK2 receptor antagonist Z-360 in combination with gemcitabine in patients with advanced pancreatic cancer Ghent University University of Antwerp
Psychometric evaluation of the FACT colorectal cancer symptom index (FCSI-9): reliability, validity, responsiveness, and clinical meaningfulness Ghent University University of Antwerp
Role of cell cycle perturbations in the combination therapy of chemotherapeutic agents and radiation Ghent University University of Antwerp
The combination of radiotherapy with chemotherapeutic agents that sensitize tumor cells to ionizing radiation has long been regarded as a promising strategy to enhance cancer therapy. Many chemotherapeutic agents interact with radiation and enhance the cytotoxic or anti-tumor effect of radiation through a number of mechanisms. These include an increase in initial radiation damage, inhibition of cellular repair, cell cycle redistribution, ...
A new dedicated beta-NMR/beta-NQR setup for LISE-GANIL KU Leuven
A new beta-NMR/beta-NQR setup is developed to study nuclear magnetic dipole moments and electric quadrupole moments at the USE fragment separator at GANIL Two key elements make the new design very powerful: the homogeneous magnet and the strong radio-frequency amplifier. The combination of both makes it possible to examine a broad spectrum of magnetic dipole and electric quadrupole moments. Several factors have an influence on the detection ...