Researcher
Thomas Naert
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry, Molecular and cell biology not elsewhere classified
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From24 Sep 2014 → Today
Projects
1 - 3 of 3
- Morphological, molecular and functional insights into the cardiovascular complications of autosomal dominant polycystic kidney diseaseFrom1 Nov 2023 → TodayFunding: BOF - postdoctoral mandates
- CRISPR/Cas9-based in vivo identification of EZH2 as a therapeutic target in desmoid tumors and small cell lung cancerFrom1 Jan 2019 → 31 Dec 2019Funding: Foundations, funds and other with scientific goal
- Identifying targets for therapy in a novel genetic Xenopus model for Familal Adenomatous PolyposisFrom1 Jan 2015 → 31 Dec 2018Funding: IWT personal funding - strategic basic research grants, IWT personal funding - specialisation scholarships
Publications
1 - 10 of 21
- Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis(2023)
Authors: Dieter Tulkens, Marthe Boelens, Thomas Naert, Marjolein Carron, Suzan Demuynck, Sylviane Dewaele, Gert Van Isterdael, David Creytens, Tim Pieters, Steven Goossens, et al.
Pages: 2404 - 2413 - Genetic variants in ARHGEF6 cause congenital anomalies of the kidneys and urinary tract in humans, mice, and frogs(2023)
Authors: V. Klämbt, F. Buerger, C. Wang, Thomas Naert, K. Richter, T. Nauth, A. C. Weiss, T. Sieckmann, E. Lai, D. Connaughton, et al.
Pages: 273 - 290 - HNF1B alters an evolutionarily conserved nephrogenic program of target genes(2023)
Authors: Kelli Grand, Martine Stoltz, Ludovica Rizzo, Ruth Roeck, Michael M. Kaminski, Gabriela Salinas, Maike Getwan, Thomas Naert, Roman Pichler, Soeren S. Lienkamp
Pages: 412 - 432 - CRISPR-SID : identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping(2021)
Authors: Thomas Naert, Dieter Tulkens, Tom Van Nieuwenhuysen, Joanna Przybyl, Suzan Demuynck, Matt van de Rijn, Mushriq Al-Jazrawe, Benjamin A. Alman, Paul Coucke, Kim De Leeneer, et al.
- Deep learning is widely applicable to phenotyping embryonic development and disease(2021)
Authors: Thomas Naert, Ozgun Cicek, Paulina Ogar, Max Burgi, Nikko-Ideen Shaidani, Michael M. Kaminski, Yuxiao Xu, Kelli Grand, Marko Vujanovic, Daniel Prata, et al.
- RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis(2020)
Authors: Thomas Naert, Dionysia Dimitrakopoulou, Dieter Tulkens, Suzan Demuynck, Rivka Noelanders, Liza Eeckhout, Gert Van Isterdael, Dieter Deforce, Christian Vanhove, Kris Vleminckx
Pages: 2692 - 2706 - CRISPR/Cas9-mediated cancer modeling and identification of cancer cell vulnerabilities in Xenopus tropicalis(2019)
Authors: Thomas Naert
- CRISPR/Cas9-mediated knockout of Rb1 in Xenopus tropicalis(2018)Series: Methods in Molecular Biology
Authors: Thomas Naert, Kris Vleminckx, Pedro G Santiago-Cardona
Pages: 177 - 193 - Cancer models in Xenopus tropicalis by CRISPR/Cas9 mediated knockout of tumor suppressors(2018)Series: Methods in Molecular Biology
Authors: Thomas Naert, Kris Vleminckx
Pages: 147 - 161 - Genotyping of CRISPR/Cas9 genome edited Xenopus tropicalis(2018)Series: Methods in Molecular Biology
Authors: Thomas Naert, Kris Vleminckx
Pages: 67 - 82