Researcher
Sofie Jacobs
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From15 Mar 2017 → 13 Dec 2021
Projects
1 - 1 of 1
- Building relevant Zika virus infection models to study neuroinvasiveness and vertical/sexual transmission and to assess the potential of novel antiviral strategiesFrom1 Mar 2017 → 25 Nov 2021Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 12
- Nek-aan-nekrace tegen arbovirussen Onderzoek en ontwikkeling van antivirale geneesmiddelen tegen terugkerende arbovirussen(2021)
Authors: Sofie Jacobs, Johan Neyts, Leen Delang
- An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models(2021)
Authors: Xin Zhang, Lana Langendries, Sofie Jacobs, Sebastiaan ter Horst, Laura Seldeslachts, Laurens Liesenborghs, Robbert Boudewijns, Hendrik Jan Thibaut, Kai Dallmeier, Greetje Vande Velde, et al.
- Favipiravir Does Not Inhibit Chikungunya Virus Replication in Mosquito Cells and Aedes aegypti Mosquitoes(2021)
Authors: Sofie Jacobs, Evelien Vanderlinden, Lieve Naesens, Leen Delang
- Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial(2021)
Authors: Laurens Liesenborghs, Isabel Spriet, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Laure-Anne Teuwen, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Ewout Landeloos, et al.
- Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains(2021)
Authors: Sofie Jacobs, Maïlis Charlotte Darmuzey, Sebastian Lequime, Leen Delang, Johan Neyts, Suzanne Kaptein
- STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters(2020)
Authors: Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne Kaptein, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, et al.
- Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity(2020)
Authors: Suzanne Kaptein, Sofie Jacobs, Lana Langendries, Laura Seldeslachts, Sebastiaan ter Horst, Laurens Liesenborghs, Bart Hens, Valentijn Vergote, Elisabeth Heylen, Xin Zhang, et al.
Pages: 26955 - 26965 - Antiviral drug discovery against arthritogenic alphaviruses: Tools and molecular targets(2020)
Authors: Rana Abdelnabi, Sofie Jacobs, Leen Delang, Johan Neyts
- Pan-viral protection against arboviruses by activating skin macrophages at the inoculation site(2020)
Authors: Leen Delang, Sofie Jacobs, Rana Abdelnabi, Johan Neyts
- A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice(2019)
Authors: Sofie Jacobs, Leen Delang, Erik Verbeken, Johan Neyts, Suzanne Kaptein