Researcher
Nick Devoogdt
- Keywords:Medicine, Applied biological sciences, biotechnology, General and logistic services
- Disciplines:Cancer therapy, Radiopharmacy, Biomarker evaluation, Nuclear imaging, Molecular diagnostics, Medical molecular engineering of nucleic acids and proteins, Medical biotechnology diagnostics, Applied immunology, Non-clinical studies, Industrial molecular engineering of nucleic acids and proteins, Cancer diagnosis
Affiliations
- Molecular Imaging and Therapy (Research group)
Member
From1 Jan 2023 → Today - Medical Imaging (Research group)
Member
From1 Jan 2011 → Today - Molecular Imaging and Therapy (Research group)
Member
From3 Jun 2024 → 31 Dec 2024 - R&D centraal (Administrative office)
Member
From3 Jun 2024 → 31 Dec 2024 - Supporting clinical sciences (Department)
Member
From1 Jan 2024 → Today - Molecular Imaging and Therapy (Research group)
Member
From1 Jan 2024 → Today - Supporting clinical sciences (Department)
Member
From1 Oct 2021 → Today - Supporting clinical sciences (Department)
Member
From8 Apr 2019 → 30 Sep 2021 - Supporting clinical sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Supporting clinical sciences (Department)
Member
From1 Mar 2013 → 31 Dec 2017 - Medical Imaging and Physical Sciences (Department)
Member
From1 Mar 2013 → 31 Dec 2013 - Medical Imaging and Physical Sciences (Department)
Member
From1 Oct 2007 → 30 Sep 2009 - FORMER_Cellular and Molecular Immunology (Research group)
Member
From1 Oct 1999 → 30 Sep 2007 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 1997 → 28 Feb 2013
Projects
1 - 10 of 41
- VYPER — Viola Yedoensis Peptide asparagine ligase (VyPAL) Enzyme-mediated generation of RadiotheranosticsFrom1 Jan 2025 → TodayFunding: FWO research project (including WEAVE projects)
- Exploiting Peptides as Protein Binders, Modulators, Inhibitors and Biomaterials for Imaging and Therapy [Exploit-PeptIT]From1 Mar 2024 → TodayFunding: BOF - projects
- Development of a bispecific immunotracer against CD8 and CD69 for enhanced non-invasive imaging of immune responses during anti-cancer immunotherapyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Development of automated enzyme-mediated bioconjugations as a technology to produce smallprotein-based radiopharmaceuFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- MATRACs: Membrane Anchoring TRAfficking ChimerasFrom1 Jan 2023 → TodayFunding: BOF - iBOF
- INVISIBLE: Investigation and inhibition of Epstein-Barr Virus immune evasion by BILF1-modulating nanobodiesFrom1 Nov 2022 → TodayFunding: FWO junior postdoctoral fellowship
- IOF Accelerator:Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)From1 Oct 2022 → 31 Mar 2024Funding: IOF - technology validation in real environment
- CASA PETIt: CAmera for Small Animal PET-ImagingFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- IOF POC Project SYNALI : Development and application of a Synthetic Nanobody LibraryFrom1 Jan 2022 → TodayFunding: IOF - technology concept exploration
- Nanobody-based AXL targeting and combination treatment for acute myeloid leukemia and multiple myelomaFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 162
- Efficient α and β- radionuclide therapy targeting fibroblast activation protein-α in an aggressive preclinical mouse tumour model(2025)
Authors: Hannelore Ceuppens, Ana Rita Pombo Antunes, Laurent Navarro, Thomas Ertveldt, Marion Berdal, Surasa Nagachinta, Kirsten De Ridder, Tony Lahoutte, Marleen Keyaerts, Nick Devoogdt, et al.
Pages: 444-457 - Development and evaluation of a single domain antibody targeting folate receptor alpha for radioligand therapy(2024)
Authors: Jonatan Dewulf, Sam Massa, Laurent Navarro, Yana Dekempeneer, Francis Santens, Hannelore Ceuppens, Karine Breckpot, Jo Van Ginderachter, Tony Lahoutte, Matthias D'Huyvetter, et al.
- Generic semi-automated radiofluorination strategy for single domain antibodies: [18F]FB-labelled single domain antibodies for PET imaging of fibroblast activation protein-α or folate receptor-α overexpression in cancer(2024)
Authors: Herlinde Dierick, Laurent Navarro, Hannelore Ceuppens, Thomas Ertveldt, Ana Rita Pombo Antunes, Marleen Keyaerts, Nick Devoogdt, Karine Breckpot, Matthias D'Huyvetter, Tony Lahoutte, et al.
- AXL as immune regulator and therapeutic target in Acute Myeloid Leukemia(2024)
Authors: Niels Vandewalle, Nathan De Beule, Ann De Becker, Elke De Bruyne, Eline Menu, Karin Vanderkerken, Karine Breckpot, Nick Devoogdt, Kim De Veirman
- Preclinical evaluation of antigen-sensitive B7-H3-targeting nanobody-based CAR-T cells in glioblastoma cautions for on-target, off-tumor toxicity(2024)
Authors: Fien Meeus, Cyprine Neba Funeh, Robin Maximilian Awad, Katty Zeven, Dorien Autaers, Ann De Becker, Ivan Van Riet, Cleo Goyvaerts, Sandra Tuyaerts, Bart Neyns, et al.
- HER2 Nanobody-Poly(rhamnose) Conjugates Efficiently Recruit Anti-Rhamnose Antibodies from Serum to the Surface of HER2-Expressing Cells(2024)
Authors: Weiwei Mu, Yong Chen, Zifu Zhong, Benoit Louage, Heleen Lauwers, Nick Devoogdt, Jurgen Haustraete, Bruno G. De Geest
Pages: 10113-10124 - Specific Imaging of CD8+ T-Cell Dynamics with a Nanobody Radiotracer against Human CD8β(2024)
Authors: Timo W M De Groof, Yoline Lauwers, Tessa De Pauw, Mohit Saxena, Cécile Vincke, Jolien Van Craenenbroeck, Catherine Chapon, Roger Le Grand, Geert Raes, Thibaut Naninck, et al.
Pages: 193-207 - Advancements in Nuclear Imaging Using radiolabeled Nanobody tracers to support Cancer Immunotherapy(2024)
Authors: Katty Zeven, Yoline Lauwers, Lynn De Mey, Jens Debacker, Tessa De Pauw, Timo W M De Groof, Nick Devoogdt
- Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery(2024)
Authors: Lukasz Mateusiak, Sam Floru, Timo W M De Groof, Janne Wouters, Noemi B Declerck, Pieterjan Debie, Simone Janssen, Katty Zeven, Karine Breckpot, Janik Puttemans, et al.
- Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties(2024)
Authors: Heleen Hanssens, Fien Meeus, Emma Lisette Gesquiere, Janik Puttemans, Yannick De Vlaeminck, Kim De Veirman, Karine Breckpot, Nick Devoogdt
Patents
1 - 10 of 10
- Biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells (Inventor)
- Anti lag3 vhhs and their use (Inventor)
- Radio-labelled antibody fragments for use in the prevention and/or treatment of cancer (Inventor)
- Anti lag3 vhhs and their use (Inventor)
- Radiolabelled antibody fragments for use in treating cancer (Inventor)
- Human pd-l1-binding immunoglobulins (Inventor)
- A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells (Inventor)
- Cd20 binding agents and uses thereof (Inventor)
- Anti-macrophage mannose receptor immunoglobulin single variable domains for targeting and in vivo imaging of tumor-associated macrophages (Inventor)
- Targeting and in vivo imaging of tumor-associated macrophages (Inventor)
Linked dataset
1 - 1 of 1