Researcher
Kiavash Movahedi
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology, Medicine
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Vrije Universiteit Brussel):Innate immunity, Inflammation, Transcriptomics, Single-cell data analysis, Neurosciences not elsewhere classified, Cancer therapy, Stem cell biology, Neurological and neuromuscular diseases
Affiliations
- Laboratory of Molecullar and Cellular Therapy (Research group)
Member
From19 Mar 2021 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 May 2023 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Nov 2020 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Nov 2020 → 30 Apr 2023 - Cellular and Molecular Immunology (Research group)
Member
From1 Sep 2020 → 31 Oct 2020 - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → 30 Aug 2020 - Faculty of Sciences and Bioengineering Sciences (Faculty)
Member
From22 Jun 2017 → 7 Sep 2017 - Van Ginderachter Lab (Research group)
Member
From1 Jan 2017 → 31 Dec 2022 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2005 → 30 Aug 2020 - Cellular and Molecular Immunology (Research group)
Member
From1 Oct 2005 → 30 Sep 2009
Infrastructure
1 - 1 of 1
Projects
1 - 6 of 6
- eveloping microglia replacement therapy to treat progranulinassociated frontotemporal dementiaFrom1 Nov 2022 → TodayFunding: FWO fellowships
- MyeCellTherapy: A novel myeloid-based cell therapy for glioblastoma, using genetically enhanced iPSCs-derived macrophages (iGEMs).From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Uncovering the dynamics of adult microglial engraftment as foundation for brain macrophage replacement therapy..From1 Jan 2021 → TodayFunding: FWO research project
- The role of stress-induced glucocorticoids in glioma development, progression and immunotherapy responsivenessFrom1 Jan 2021 → TodayFunding: FWO research project
- Dissecting the neural-immune interactions of microglia in health and disease.From1 Jan 2016 → 31 Dec 2016Funding: FWO research grant KAN
- Attract Brains for Brussels: Dissecting the neuro-immune interactions of microglia in health and disease.From1 Sep 2015 → 31 Aug 2020Funding: Brussels Capital Region
Publications
1 - 10 of 48
- Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons(2023)
Authors: Lien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Lieve Moons, et al.
- Overcoming the immune suppressive nature of glioblastoma by leveraging the surgical intervention - current status and future perspectives(2023)
Authors: Johnny Duerinck, Sandra Tuyaerts, Kiavash Movahedi, Bart Neyns
- The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus(2023)
Authors: Stephanie M Robert, Benjamin C Reeves, Emre Kiziltug, Phan Q Duy, Jason K Karimy, M Shahid Mansuri, Arnaud Marlier, Garrett Allington, Ana B W Greenberg, Tyrone DeSpenza, et al.
Pages: 764-785.e21 - Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting(2023)
Authors: Marco Erreni, Francesca D'Autilia, Roberta Avigni, Evangelia Bolli, Sana M Arnouk, Kiavash Movahedi, P Debie, Achille Anselmo, Raffaella Parente, Cécile Vincke, et al.
Pages: 355-373 - Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq(2022)
Authors: Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van Den Hoecke, Isabelle Scheyltjens, et al.
- Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape(2022)
Authors: James Boot, Gabriel Rosser, Dailya Kancheva, Claire Vinel, Yau Mun Lim, Nicola Pomella, Xinyu Zhang, Loredana Guglielmi, Denise Sheer, Michael Barnes, et al.
- Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation(2022)
Authors: Karen De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Jonathan Bastos, Mónica Vara Pérez, Leen Ali, Myrthe Mampay, Lauren Deneyer, et al.
Pages: 2085-2102.e9 - Single-cell RNA and protein profiling of immune cells from the mouse brain and its border tissues(2022)
Authors: Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Daliya Kancheva, Jonathan Bastos, Mónica Vara Pérez, Ana Rita Pombo Antunes, Liesbet Martens, Charlotte L Scott, Jo A Van Ginderachter, et al.
Pages: 2354-2388 - Macrophage compartmentalization in the brain and cerebrospinal fluid system(2022)
Authors: David A D Munro, Kiavash Movahedi, Josef Priller
- Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha(2021)
Authors: Karen De Vlaminck, Ema Romao, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, et al.
Patents
1 - 3 of 3
- Targeting and in vivo imaging of tumor-associated macrophages (Inventor)
- Anti-macrophage mannose receptor immunoglobulin single variable domains for targeting and in vivo imaging of tumor-associated macrophages (Inventor)
- Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages (Inventor)