Researcher
Jolien De Wyn
- Disciplines:Transcription and translation, Cancer biology, Epigenetics, Paediatrics, Genetics, Cell death, Cell therapy, Cell division, Posttranslational modifications, Cell growth and development, Cancer therapy
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 16 Aug 2021 - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2014 → 30 Sep 2018
Publications
1 - 10 of 10
- HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening(2024)
Authors: Carolina de Carvalho Nunes, Jasper Anckaert, Fanny De Vloed, Jolien De Wyn, Kaat Durinck, Jo Vandesompele, Franki Speleman, Vanessa Vermeirssen
- MEIS2 is an adrenergic core regulatory transcription factor involved in early initiation of TH-MYCN-driven neuroblastoma formation(2021)
Authors: Jolien De Wyn, Mark W. Zimmerman, Nina Weichert-Leahey, Carolina de Carvalho Nunes, Belamy B. Cheung, Brian J. Abraham, Anneleen Beckers, Pieter-Jan Volders, Bieke Decaesteker, Daniel R. Carter, et al.
- TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets(2018)
Authors: Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M Dolman, Wouter Van Loocke, Moritz Gartlgruber, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, et al.
- The RRM2-PHF6 complex protects neuroblastoma cells from DNA damage accumulation to install a replication stress resistance phenotype(2018)
Authors: Sofia Zanotti, Emmy Dolman, Aline Eggermont, Bieke Decaesteker, Pauline Depuydt, Jolien De Wyn, Geertrui Denecker, Winnok De Vos, Matthias Fischer, Jan Molenaar, et al.
Number of pages: 1 - An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Authors: Suzanne Vanhauwaert, Carina Leonelli, Sara De Brouwer, Jolien De Wyn, Anneleen Beckers, Neuroblastoma Research consortium, Karen Sermon
Number of pages: 1 - The BRIP1/FANCJ DNA helicase is a druggable 17q driver oncogene involved in G-quadruplex induced replicative stress resistance in neuroblastoma
Authors: Suzanne Vanhauwaert, Annelies Fieuw, Carina Leonelli, Bieke Decaesteker, Jolien De Wyn, Pauline Depuydt, Sara De Brouwer, Shuning He, Thomas Look
Number of pages: 1 - SOX11 is a transcriptional circuit dosage sensitive transcription factor controlling SWI/SNF components
Authors: Bieke Decaesteker, Sara De Brouwer, Geertrui Denecker, Fanny De Vloed, Wouter Van Loocke, Suzanne Vanhauwaert, Pauline Depuydt, Moritz Gartlgruber, Jolien De Wyn, Genevieve Laureys, et al.
Number of pages: 1 - SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastomaVolume: 58
Authors: Bieke Decaesteker, Sara De Brouwer, Fanny De Vloed, Geertrui Denecker, Suzanne Vanhauwaert, Jolien De Wyn, Pauline Depuydt, Patrick Reynolds, Jo Vandorpe, Jan Koster, et al.
Number of pages: 1 - SOX11 acts as part of the MYCN-WEE1 regulatory protein complex implicated in neuroblastoma
Authors: Bieke Decaesteker, Sara De Brouwer, Fanny De Vloed, Geertrui Denecker, Suzanne Vanhauwaert, Jolien De Wyn, Pauline Depuydt, Jo Vandorpe, Jan Koster, Sara Ek
Number of pages: 1 - An embryonic stem cell activated FOXM1 transcriptional program marks ultra-high-risk primary neuroblastoma patients for FDI-6 small molecule inhibition
Authors: Suzanne Vanhauwaert, Carina Leonelli, Sara De Brouwer, Jolien De Wyn, Anneleen Beckers, Karen Sermon
Number of pages: 1