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Project
A role for B cells in immunomodulatory treatment of multiple sclerosis.
Several new treatments for multiple sclerosis (MS) have entered the market or are under development. The crucial question for the neurologist and person with MS now is the choice of the most appropriate treatment. To facilitate an informed decision, we will determine the mechanism of action of frequently used immunomodulatory treatments for MS and clarify especially the role of a subset of immune cells, the B cells, herein. Subsequently, we will investigate whether genetic factors can predict an individuals response to treatment.
Date:1 Jan 2015 → 31 Dec 2015
Keywords:MS, B cells, Multiple sclerosis, personalized medicine, immunomodulation, translational research, immunology
Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences