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Innate imprinting of resident alveolar macrophages by allergic airway inflammation: mechanism and consequences for asthma exacerbation (3F013813)

In a mouse model of asthma, resident alveolar macrophages showed an increased inflammatory reactivity upon post-infection of the asthmatic lung. This project aims to elucidate the mechanism underlying the altered macrophage innate functionality and hereby to enable interference with asthma exacerbation.

Date:1 Oct 2013  →  30 Sep 2017
Keywords:exacerbation, asthma, mouse model, Inflammation, alveolar macrophages