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Immunoediting and immune evasion mechanisms in the treated and untreated cancer genome

Tumour-immune interactions during tumour evolution result in immunoediting and immune evasion. The goal of this project is to use large cancer genome databases to identify the underlying genomic alterations, in both the untreated cancer genome and following treatment with immunomodulating agents. Results can be exploited to predict differential responses to cancer immunotherapy.

Date:1 May 2019  →  Today
Keywords:immune evasion, immunoediting, tumour evolution, Cancer, somatic mutations
Disciplines:Oncology not elsewhere classified, Bioinformatics and computational biology not elsewhere classified