Hyperlipidemia and the consequences on oocyte and embryo quality. A combined bovine in vivo and in vitro model for human infertility research.

Hypercholesterolemia is a human disorder and it has been associated with an unhealthy eat pattern. This combined in vivo and in vitro bovine model will elucidate the effect of nutritionally induced hypercholesterolemia on oocyte and embryo quality. In earlier work we showed that the metabolic changes in dairy cows early post partum and their consequences on oocyte and follicle quality is a valuable model for research in human infertility.

Keywords:EMBRYO, IN VITRO FERTILISATION, METABOLISM, HYPERCHOLESTEROLEMIA

Disciplines:Animal biology, Genetics, Endocrinology and metabolic diseases, Gynaecology and obstetrics, Nursing, Veterinary medicine