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Patent
Methods and media for preparing cells for healing bone and joint disorders
The invention relates to in vitro methods of inducing hypertrophy in chondrogenic cells comprising the step of incubating aggregates of chondrogenic cells in a medium comprising BMP4 or BMP2, a Wnt agonist and a thyroid hormone. The invention further relates to the medical use of cells obtained by this method to repair bone and joint disorders.
Patent Publication Number: WO2018114832
Year filing: 2017
Year approval: 2019
Year publication: 2018
Status: Requested
URI: link to Espacenet
Technology domains: Biotechnology
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven