Organisation
Experimental Laboratory Immunology
Division
This laboratory studies the regulation of the immune response to Streptococcus pneumoniae, immunodeficiencies (with particular interest on innate immunity), and autoimmunity (with particular interest on serological markers).
Current researchers
1 - 10 of 14 results
- Xavier Bossuyt (Responsible)
- Louanne Ampofo (Member)
- Lina Ancheva (Member)
- Lise Boon (Member)
- Heleen Borgers (Member)
- Xavier Bossuyt (Member)
- Maaike Cockx (Member)
- Kris Covens (Member)
- Glynis Frans (Member)
- Katrijn Op De Beéck (Member)
Projects
1 - 10 of 26 results
- Complementarity determining region-based immunoprofiling of rheumatoid arthritis.From1 Jan 2021 → TodayFunding: FWO research project
- Development and clinical validation of a multiplexed massspectrometry- based assay to improve diagnosis of Rheumatoid ArthritisFrom1 Jan 2021 → TodayFunding: FWO Applied Biomedical Research (TBM)
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → TodayFunding: BOF - scientific equipment program
- Tumor necrosis factor Receptor-Associated Factors in signal transduction and susceptibility to infection.From1 Jan 2021 → TodayFunding: FWO research project
- Mass spectrometry-based autoantibody tests for specific diagnosis of autoimmune diseasesFrom1 Oct 2020 → TodayFunding: IOF - technology validation in lab
- Translational research related to Corona-Covid 19From1 Apr 2020 → TodayFunding: IOF - technology validation in lab
- ProFiLE:Standardized multi-parameter flow cytometry for early diagnosis, risk assessment and optimized treatment in primary immunodeficiencyFrom1 Oct 2019 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Development and validation of an assay to quantify anti-dsDNA antibody levels and avidity for more accurate diagnosis and monitoring of SLEFrom1 Oct 2019 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Characterisation of the genetic and immunological factors controlling appropriate responses to infections in childrenFrom1 Oct 2018 → TodayFunding: BOF - Concerted Research Project from 1994
- Identification, validation and pathogenicity of novel autoantibodies in idiopathic inflammatory myopathy.From1 Oct 2018 → TodayFunding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 319 results
- NCKAP1L defects lead to a novel syndrome combining immunodeficiency, lymphoproliferation, and hyperinflammation(2020)
Authors: Carla Noemi Castro, Michelle Rosenzwajg, Raphael Carapito, Mohammad Shahrooei, Martina Konantz, Amjad Khan, Zhichao Miao, Miriam Gross, Thibaud Tranchant, Mirjana Radosavljevic, et al.
Number of pages: 22 - Current laboratory and clinical practices in reporting and interpreting anti-nuclear antibody indirect immunofluorescence (ANA IIF) patterns: results of an international survey(2020)
Authors: Lieve Van Hoovels, Sylvia Broeders, Edward KL Chan, Luis Andrade, Wilson de Melo Cruvinel, Jan Damoiseaux, Markku Viander, Manfred Herold, Wim Coucke, Ingmar Heijnen, et al.
Number of pages: 12 - Understanding and interpreting antinuclear antibody tests in systemic rheumatic diseases(2020)
Authors: Xavier Bossuyt, Ellen De Langhe, Maria Orietta Borghi, Pier Luigi Meroni
Pages: 715 - 726Number of pages: 12 - International Consensus on Antineutrophil Cytoplasm Antibodies Testing in Eosinophilic Granulomatosis with Polyangiitis(2020)
Authors: Sergey Moiseev, Xavier Bossuyt, Yoshihiro Arimura, Daniel Blockmans, Elena Csernok, Jan Damoiseaux, Giacomo Emmi, Luis Felipe Flores-Suarez, Bernhard Hellmich, David Jayne, et al.
Pages: 1360 - 1372Number of pages: 13 - Standardisation of PR3-ANCA and MPO-ANCA: evaluation of certified reference materials(2020)
Authors: Xavier Bossuyt, Doreen Dillaerts, Michael Mahler, Dirk Roggenbuch, Ulrich Leinfelder, Friederike Hammar, Wolfgang Schlumberger, Nina Olschowka, Jan Damoiseaux
Pages: 1520 - +Number of pages: 3 - Detection of anti-Mi-2 autoantibodies before dermatomyositis-specific manifestations.(2020)
Authors: Jean-Baptiste Vulsteke, Daniël Blockmans, Veronique Moons, Sara Vijgen, Xavier Bossuyt, Ellen De Langhe
Pages: e60 - e62 - Detection of circulating anti-skin antibodies by indirect immunofluorescence and by ELISA: a comparative systematic review and meta-analysis(2020)
Authors: Otto Van de Gaer, Petra De Haes, Xavier Bossuyt
Pages: 1623 - 1633Number of pages: 11 - Quality and best practice in medical laboratories: specific requests for autoimmunity testing(2020)
Authors: Ulrich Sack, Xavier Bossuyt, Hristina Andreeva, Peter Antal-Szalmas, Nicola Bizzaro, Dimitrios Bogdanos, Elena Borzova, Karsten Conrad, Marie-Agnes Dragon-Durey, Catharina Eriksson, et al.
Number of pages: 9 - Determination of free light chains: assay-dependent differences in interpretation.(2020)
Authors: Xavier Bossuyt, Koen Poesen, Ben Sprangers, Martin Reynders, Martine Vercammen, Michel Delforge
Pages: e69 - e71 - Likelihood Ratios as Value Proposition for Diagnostic Laboratory Tests(2020)
Authors: Walter Fierz, Xavier Bossuyt
Pages: 1061 - 1069Number of pages: 9