Pathogenesis and transmission of influenza in pigs (FLUPIG) (FLUPIG)

Pandemic influenza viruses originate from wild birds, but must adapt to efficient replication and transmission in humans to cause a pandemic. Pigs are considered important intermediate hosts where adaptation can occur. FLUPIG studies the genetic, host and environmental factors required for adaptation to mammals. Also, the role of cross-protective immunity on the occurrence and severity of a pandemic is studied.