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Project
Mutations in DNA double strand break repairgenes as biomarkers for breast cancer predisposition
The aim of this project is: - identification of mutations in DNA double strand break repair genes, that result in a radiosensitive phenotype and are linked to breast cancer predisposition - the development of useful predictive biomarkers to evaluate the individual breast cancer risk in a healthy female population.
Date:1 Jan 2008 → 31 Dec 2010
Keywords:mutation, breast cancer, SNP, chromosomal radiosensitivity, DNA repair genes, biomarker, RNAinterference
Disciplines:Laboratory medicine, Molecular and cell biology, Microbiology, Medical systems biology, Public health sciences, Veterinary medicine, Public health care, Public health services