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Project
Evaluation of 5-HT4 receptor agonism in central and peripheral in vitro models
Newly synthetized 5-HT4 receptor agonists are tested in different electrophysiological protocols in rat hippocampal brain slices. Effects at peripheral 5-HT4 receptors are tested in rat esophageal muscularis mucosae, guinea pig proximal colon and porcine proximal stomach and left atrium.
Date:1 Dec 2010 → 31 May 2013
Keywords:atrium, 5-HT4 receptor, hippocampus, intestine, stomach
Disciplines:Developmental psychology and ageing, Neurosciences, Gastro-enterology and hepatology, Cognitive science and intelligent systems, Biological and physiological psychology