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Publication
Unraveling the Rewired Metabolism in Lung Cancer Using Quantitative NMR Metabolomics
Journal Contribution - Review Article
Lung cancer cells are well documented to rewire their metabolism and energy production networks to enable proliferation and survival in a nutrient-poor and hypoxic environment. Although metabolite profiling of blood plasma and tissue is still emerging in omics approaches, several techniques have shown potential in cancer diagnosis. In this paper, the authors describe the alterations in the metabolic phenotype of lung cancer patients. In addition, we focus on the metabolic cooperation between tumor cells and healthy tissue. Furthermore, the authors discuss how metabolomics could improve the management of lung cancer patients.
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN: 1661-6596
Issue: 10
Volume: 23
Publication year:2022
Keywords:NMR (nuclear magnetic resonance), lung cancer, metabolism, Humans, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Phenotype, Lung Neoplasms, Metabolomics
Accessibility:Open