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Patent

IMPROVED TRANSFECTION OF EUKARYOTIC CELLS WITH LINEAR POLYNUCLEOTIDES BY ELECTROPORATION

The present invention provides an improved method for gene delivery in eukaryontic cells by electroporation, preferably in human hematopoietic cells, particular dendritic cells. The method of the invention is superior to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for gene delivery, including tumor antigen loading of dendritic cells.
Patent Publication Number: EP1397500
Year filing: 2002
Year approval: 2014
Year publication: 2014
Status: Assigned
Technology domains: Pharmaceuticals
Validated for IOF-key: Yes
Attributed to: Associatie Universiteit & Hogescholen Antwerpen