Silicone Wristbands as personal ExposurE monitor to Predict the internal exposure to emerging contaminants (SWEEP).

Emerging contaminants (ECs) are a group of anthropogenic chemicals widely distributed in the environment. These chemicals are of growing concern due to their ubiquitous presence in the environment and potential hazardous effect to humans. Thus, it is critical to investigate the levels and patterns of exposure to ECs in the environment/human to provide a better assessment of the health risks. Since people are exposed to a mixture of complex chemicals in the environment, the assessment of personal exposure is the key to link the external and internal exposure and eventually the health effects. Silicone wristband represents the aggregate personal exposure of multiple exposure pathways, which would be ideal to predict the internal exposure. In this study, we will use the silicone wristbands as sampler to monitor the external exposure to ECs on the individual level, quantify the external and internal exposure concentration and then use a refined model to predict the internal exposure concentrations from the silicone wristband exposure data. We will also use suspect screening techniques to explore and identify new ECs using silicone wristbands to aid future exposure studies. This study aims to provide new insights into the exposure levels and patterns, gain better understanding for the correlation between external and internal exposure and refine and develop a method to predict the internal exposure dose thus simplify the exposure assessment in the general population.

Keywords:HUMAN EXPOSURE

Disciplines:Analytical separation and detection techniques, Instrumental methods, Environmental chemistry, Other environmental sciences not elsewhere classified

Project type:Collaboration project