Organisation
Immunoparasitology (Rega Institute)
Lab
The aim of our malaria research program is to investigate the immunological and molecular mechanisms leading to complicated malaria and to design potential therapies.
Current researchers
1 - 7 of 7 results
- Philippe Van den Steen (Responsible)
- Alia Fazal Salom (Member)
- Emilie Pollenus (Member)
- Hendrik Possemiers (Member)
- Rebecca Sadler (Member)
- Philippe Van den Steen (Member)
- Leen Vandermosten (Member)
Projects
1 - 10 of 16
- CD8+ T cell mediated pathogenesis in malariaFrom7 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Leukocyte trafficking in the resolution of inflammationFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Mechanisms of disease resolution in severe malariaFrom19 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Immunopathogenesis of malaria-associated acute kidney injuryFrom12 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Reducing severe malaria related child mortality in the Democratic Republic of Congo (DRC) by improving the management and control of malaria associated kidney injury (MAKI)From1 Sep 2023 → TodayFunding: VLIR-UOS South Initiatives
- Disease resolution mechanisms and interrelation with dysmetabolism in severe malariaFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Inflammation and dysmetabolism in malariaFrom23 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Glucocorticoid regulation of systemic immunometabolism in malariaFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- The interrelation between endogenous glucocorticoids, inflammation and metabolic disturbances in malariaFrom1 Oct 2019 → 18 Oct 2022Funding: FWO fellowships
Publications
1 - 10 of 83
- Inhibition of enzymatic degradation of adhesive-dentin interfaces(2009)
Authors: Jan De Munck, Philippe Van den Steen, Atsushi Mine, Kirsten Van Landuyt, André Poitevin, Ghislain Opdenakker, Bart Van Meerbeek
Pages: 1101 - 1106 - Contribution of the Ly49E natural killer receptor in the immune response to plasmodium berghei infection and control of hepatic parasite development(2014)
Authors: Philippe Van den Steen
- Chemically synthesized matrix metalloproteinase and agiogenesis-inhibiting peptides as anticancer agents(2014)
Authors: Philippe Van den Steen, Ghislain Opdenakker
Pages: 483 - 94 - Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance(2015)
Authors: Philippe Van den Steen
Pages: 893 - 903 - Matrix metalloproteinase-9 induces a pro-angiogenic profile in chronic lymphocytic leukemia cells(2019)
Authors: Philippe Van den Steen, Ghislain Opdenakker
Pages: 198 - 204 - Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen(2014)
Authors: Estefania Ugarte Berzal, Philippe Van den Steen, Ghislain Opdenakker
Pages: 185 - 199 - "Reverse degradomics", monitoring of proteolytic trimming by multi-CE and confocal detection of fluorescent substrates and reaction products(2009)
Authors: Helene Piccard, Paul Proost, Philippe Van den Steen, Jo Van Damme, Ghislain Opdenakker
Pages: 2366 - 2377 - Experimental malaria-associated acute kidney injury is independent of parasite sequestration and resolves upon antimalarial treatment(2022)
Authors: Hendrik Possemiers, Emilie Pollenus, Philippe Van den Steen
- Zymography methods for visualizing hydrolytic enzymes(2013)
Authors: Jennifer Vandooren, Philippe Van den Steen, Ghislain Opdenakker
Pages: 211 - 220 - Matrix metalloproteinases as therapeutic targets in protozoan parasitic infections(2012)
Authors: Ghislain Opdenakker, Philippe Van den Steen
Pages: 257 - 279