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Project
Role of dendritic cells in Th1/Th17-mediated immune diseases.
Dendritic cells (DCs) are central mediators that keep the balance between immunity to foreign antigens and immune tolerance to self-proteins. Disruption of this balance may lead to disease. We aim to unravel the role of DCs in T-helper (Th)1/Th17-mediated immune diseases (including inflammatory bowel disease, multiple sclerosis, cardiovascular disease and rheumatoid arthritis), with the purpose to design novel DC-targeted therapeutic strategies.
Date:1 Jan 2013 → 31 Dec 2016
Keywords:IMMUNE TOLERANCE, INFLAMMATORY DISEASE, TH1/TH17 CELLS, DENDRITIC CELLS
Disciplines:Evolutionary biology, General biology, Immunology, Social medical sciences