The study of the removal of uremic toxins and their kinetic behaviour in order to optimise blood purifying techniques

Patients with renal failure retain a large variety of uremic retention solutes and are currently treated with a blood purifying technique like hemodialysis. To optimise this treatment, kinetic models, calibrated with clinical data, were developed, simulating solute transport in between different virtual body compartments. These models were further used to simulate different dialysis strategies.