Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia.

Congenital diaphragmatic hernia (CDH) can be associated with Genetic or structural anomalies with poor prognosis. In isolated cases, survival is dependent on the degree of lung hypoplasia and liver position. Cases Should be referred in utero to tertiary care centers familiar with this condition both for prediction of outcome as well as timed delivery. The best validated prognostic indicator is the lung area to head Circumference ratio. Ultrasound is used to measure the lung area of the index case, which is then expressed as a proportion of what is expected normally (observed/expected LHR). When O/E LHR is

Publication year:2008

Keywords:congenital diaphragmatic hernia, pulmonary hypoplasia, lung-to-head ratio, fetal tracheal occlusion, Female, Fetal Organ Maturity, Fetoscopy, Hernia, Diaphragmatic, Hernias, Diaphragmatic, Congenital, Humans, Lung, Pregnancy, Treatment Outcome, Ultrasonography, Prenatal

Accessibility:Open