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Publication

'NOTCHing up' the in vitro production of dendritic cells

Journal Contribution - Journal Editorial

Two studies show that adding NOTCH ligands to Flt3L cultures increases the yield of cDC1s from mouse and human progenitors. Moreover, these NOTCH-DCs more closely resemble in vivo DCs transcriptionally and functionally. This will be extremely valuable for studying DCs in vitro and for further developing autologous DC-based antitumor vaccinations.
Journal: TRENDS IN IMMUNOLOGY
ISSN: 1471-4981
Issue: 10
Volume: 39
Pages: 765 - 767
Publication year:2018
Accessibility:Closed